TICAM1
TIR domain-containing adapter molecule 1 is a protein in humans that is encoded by TICAM1 gene. Involved in innate immunity against invading pathogens. Adapter used by TLR3 and TLR4 (through TICAM2) to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis. Ligand binding to these receptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment of the effector proteins TBK1, TRAF6 and RIPK1, which in turn, lead to the activation of transcription factors IRF3 and IRF7, NF-kappa-B and FADD respectively.
TICAM1 Antibodies
TICAM1 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA023532KA01HU | TICAM1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA544544 | TICAM1 Antibody | Human | WB,ELISA |
TICAM1 Proteins
TICAM1 Proteins for Bos taurus (Bovine)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP678140BO CSB-EP678140BO CSB-BP678140BO CSB-MP678140BO CSB-EP678140BO-B |
Recombinant Bovine TIR domain-containing adapter molecule 1 (TICAM1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TICAM1 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP767320MO1 CSB-EP767320MO1 CSB-BP767320MO1 CSB-MP767320MO1 CSB-EP767320MO1-B |
Recombinant Mouse TIR domain-containing adapter molecule 1 (Ticam1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TICAM1 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP811598HU1 CSB-EP811598HU1 CSB-BP811598HU1 CSB-MP811598HU1 CSB-EP811598HU1-B |
Recombinant Human TIR domain-containing adapter molecule 1 (TICAM1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TICAM1 Proteins for Homo sapiens(Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-CF811598HU | Recombinant Human TIR domain-containing adapter molecule 1 (TICAM1) | in vitro E.coli expression system |
| CSB-CF811598HUe1 | Recombinant Human TIR domain-containing adapter molecule 1 (TICAM1) | in vitro E.coli expression system |
