TEC
Tyrosine-protein kinase Tec is a protein in humans that is encoded by TEC gene. Non-receptor tyrosine kinase that contributes to signaling from many receptors and participates as a signal transducer in multiple downstream pathways, including regulation of the actin cytoskeleton. Plays a redundant role to ITK in regulation of the adaptive immune response. Regulates the development, function and differentiation of conventional T-cells and nonconventional NKT-cells. Required for TCR-dependent IL2 gene induction. Phosphorylates DOK1, one CD28-specific substrate, and contributes to CD28-signaling. Mediates signals that negatively regulate IL2RA expression induced by TCR cross-linking. Plays a redundant role to BTK in BCR-signaling for B-cell development and activation, especially by phosphorylating STAP1, a BCR-signaling protein.
TEC Proteins
TEC Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP023367MO CSB-EP023367MO CSB-BP023367MO CSB-MP023367MO CSB-EP023367MO-B |
Recombinant Mouse Tyrosine-protein kinase Tec (Tec) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TEC Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP023367HU CSB-EP023367HU CSB-BP023367HU CSB-MP023367HU CSB-EP023367HU-B |
Recombinant Human Tyrosine-protein kinase Tec (TEC) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
