TEAD2
Transcriptional enhancer factor TEF-4 is a protein in humans that is encoded by TEAD2 gene. Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3'). May be involved in the gene regulation of neural development. Binds to the M-CAT motif.
TEAD2 Antibodies
TEAD2 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA070034 | TEAD2 Antibody | Human,Mouse | WB, IHC, IF, ELISA |
TEAD2 Proteins
TEAD2 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP023364MO CSB-EP023364MO CSB-BP023364MO CSB-MP023364MO CSB-EP023364MO-B |
Recombinant Mouse Transcriptional enhancer factor TEF-4 (Tead2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TEAD2 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP613597HU1 CSB-BP613597HU1 CSB-MP613597HU1 CSB-EP613597HU1-B |
Recombinant Human Transcriptional enhancer factor TEF-4 (TEAD2), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP613597HU1 | Recombinant Human Transcriptional enhancer factor TEF-4 (TEAD2), partial | E.coli |
| CSB-EP613597HU2 | Recombinant Human Transcriptional enhancer factor TEF-4 (TEAD2), partial | E.coli |
| CSB-EP613597HU2c7 | Recombinant Human Transcriptional enhancer factor TEF-4 (TEAD2), partial | E.coli |
| CSB-EP613597HU2g5 | Recombinant Human Transcriptional enhancer factor TEF-4 (TEAD2), partial | E.coli |
| CSB-EP613597HU2d7 | Recombinant Human Transcriptional enhancer factor TEF-4 (TEAD2), partial | E.coli |
