TAGLN2
TAGLN2，即轉(zhuǎn)膠蛋白2，別名HA1756、Transgelin-2。它是一種肌動(dòng)蛋白細(xì)胞骨架結(jié)合蛋白家族的重要成員，廣泛表達(dá)于多種組織細(xì)胞中。
TAGLN2的作用機(jī)制涉及調(diào)節(jié)細(xì)胞形態(tài)、運(yùn)動(dòng)和細(xì)胞轉(zhuǎn)化，通過(guò)直接結(jié)合肌動(dòng)蛋白微絲結(jié)構(gòu)影響細(xì)胞骨架的重塑，進(jìn)而參與細(xì)胞形態(tài)轉(zhuǎn)化、細(xì)胞遷移運(yùn)動(dòng)、細(xì)胞分化及增殖凋亡等功能調(diào)控。
TAGLN2在腫瘤細(xì)胞惡性表型中的潛在功能受到研究者關(guān)注，它不僅與肌動(dòng)蛋白骨架緊密連接調(diào)控細(xì)胞運(yùn)動(dòng)，還在細(xì)胞核中表達(dá)，可能通過(guò)直接調(diào)控相關(guān)基因的表達(dá)而影響細(xì)胞表型。TAGLN2的表達(dá)增加與腫瘤等級(jí)升高、預(yù)后不良相關(guān)，其在腫瘤發(fā)展中的作用使其成為潛在的分子治療靶點(diǎn)。
熱銷產(chǎn)品
Recombinant Human Transgelin-2 (TAGLN2) (CSB-EP023106HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP023106HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) TAGLN2.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP023106HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) TAGLN2.
TAGLN2 Antibody (CSB-PA023106DSR1HU)
驗(yàn)證數(shù)據(jù)
Western blot
All lanes: TAGLN2 antibody at 4.04µg/ml
Lane 1: 293T whole cell lysate
Lane 2: K562 whole cell lysate
Lane 3: MCF-7 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 23, 25 kDa
Observed band size: 23 kDa
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA023106DSR1HU at dilution of 1:100
Human Transgelin-2(TAGLN2) ELISA kit (CSB-EL023106HU)
驗(yàn)證數(shù)據(jù)
貨號(hào)：CSB-EL023106HU
規(guī)格：96T/48T
靈敏度：0.078 ng/mL
檢測(cè)范圍：0.312 ng/mL-20 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
TAGLN2 Antibodies
TAGLN2 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA023106GA01HU | TAGLN2 Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA209872 | TAGLN2 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA121037 | TAGLN2 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA023106DSR1HU | TAGLN2 Antibody | Human | ELISA, WB, IHC |
| CSB-PA023106DSR2HU | TAGLN2 Antibody | Human | ELISA, WB, IHC |
TAGLN2 Proteins
TAGLN2 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP023106HU CSB-BP023106HU CSB-MP023106HU CSB-EP023106HU-B |
Recombinant Human Transgelin-2 (TAGLN2) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP023106HU | Recombinant Human Transgelin-2 (TAGLN2) | E.coli |
| CSB-EP023106HUa0 | Recombinant Human Transgelin-2 (TAGLN2) | E.coli |
TAGLN2 ELISA Kit
TAGLN2 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL023106HU | Human Transgelin-2(TAGLN2) ELISA kit | serum, plasma, cell lysates | 0.078 ng/mL |
