SMARCD2
SMARCD2，即SWI/SNF相關矩陣相關蛋白D2，別名INI1、hSNF2α、BAF47等。它是一種由SMARCD2基因編碼的核蛋白，屬于SWI/SNF染色質重塑復合體家族成員。SMARCD2的作用機制涉及其ATP酶活性，通過改變染色質結構，促進轉錄因子的DNA結合，影響基因表達。SMARCD2在細胞增殖、分化、腫瘤抑制等多種生物學過程中發揮作用。SMARCD2的功能異常與多種疾病有關，尤其是在癌癥中，如成神經管細胞瘤、成視網膜細胞瘤等，SMARCD2的突變或缺失與腫瘤的發生發展密切相關。
熱銷產品
SMARCD2 Antibody (CSB-PA846114LA01HU)
驗證數據
Western Blot
Positive WB detected in: Raw264.7 whole cell lysate
All lanes: SMARCD2 antibody at 4.9μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 59, 58, 56 kDa
Observed band size: 59 kDa
IHC image of CSB-PA846114LA01HU diluted at 1:500 and staining in paraffin-embedded human cervical cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
SMARCD2 Antibodies
SMARCD2 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA021809GA01HU | SMARCD2 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA846114LA01HU | SMARCD2 Antibody | Human, Mouse | ELISA, WB, IHC |
| CSB-PA846114LB01HU | SMARCD2 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA846114LC01HU | SMARCD2 Antibody, FITC conjugated | Human | |
| CSB-PA846114LD01HU | SMARCD2 Antibody, Biotin conjugated | Human | ELISA |
SMARCD2 Proteins
SMARCD2 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP846114HU CSB-EP846114HU CSB-BP846114HU CSB-MP846114HU CSB-EP846114HU-B |
Recombinant Human SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 (SMARCD2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
