RYR1
RYR1蛋白，全稱為Ryanodine Receptor 1，在肌肉細胞內質網上充當鈣離子釋放通道，對肌肉收縮過程至關重要。該蛋白也被稱為RYR-1、Ryr、skrr等。RYR1蛋白的主要功能是調節肌肉細胞內鈣離子的釋放，從而觸發肌肉收縮。在肌肉收縮過程中，鈣離子通過RYR1蛋白從內質網釋放到細胞質中，進而激活肌肉收縮。RYR1蛋白與多種疾病的發生發展密切相關，包括惡性高熱、中樞性核心疾病、King-Denborough綜合征和先天性肌病等。這些疾病都與RYR1蛋白的突變或功能異常有關。
針對RYR1蛋白相關疾病的治療，目前尚無特效藥物。然而，隨著對RYR1蛋白功能和相關疾病認識的不斷深入，越來越多的研究人員開始關注RYR1蛋白的藥物研發。例如，一些研究機構正在開發針對RYR1蛋白的抑制劑，以減少鈣離子釋放，從而緩解相關疾病癥狀。此外，還有一些研究機構正在探索基因治療等新的治療策略，以糾正RYR1蛋白的突變，從而治療相關疾病。
熱銷產品
Recombinant Human Ryanodine receptor 1 (RYR1), partial (CSB-EP020619HUb0)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
驗證數據
Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: Mouse brain tissue, Primary antibody: CSB-PA050519(RYR1 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes
RYR1 Antibodies
RYR1 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA020619LC01HU | RYR1 Antibody, FITC conjugated | Human | |
| CSB-PA020619LA01HU | RYR1 Antibody | Human | ELISA, IF |
| CSB-PA050519 | RYR1 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA243333 | RYR1 Antibody | Human,Mouse,Rat | ELISA,WB |
RYR1 Proteins
RYR1 Proteins for Oryctolagus cuniculus (Rabbit)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP020619RB CSB-EP020619RB CSB-BP020619RB CSB-MP020619RB CSB-EP020619RB-B |
Recombinant Rabbit Ryanodine receptor 1 (RYR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
RYR1 Proteins for Sus scrofa (Pig)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP020619PI CSB-EP020619PI CSB-BP020619PI CSB-MP020619PI CSB-EP020619PI-B |
Recombinant Pig Ryanodine receptor 1 (RYR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
RYR1 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP020619HU CSB-BP020619HU CSB-MP020619HU CSB-EP020619HU-B |
Recombinant Human Ryanodine receptor 1 (RYR1), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP020619HU | Recombinant Human Ryanodine receptor 1 (RYR1), partial | E.coli |
| CSB-EP020619HUb0 | Recombinant Human Ryanodine receptor 1 (RYR1), partial | E.coli |
| CSB-EP020619HU1 | Recombinant Human Ryanodine receptor 1 (RYR1), partial | E.coli |
RYR1 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP020619MO CSB-EP020619MO CSB-BP020619MO CSB-MP020619MO CSB-EP020619MO-B |
Recombinant Mouse Ryanodine receptor 1 (Ryr1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
RYR1 Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP020619RA CSB-EP020619RA CSB-BP020619RA CSB-MP020619RA CSB-EP020619RA-B |
Recombinant Rat Ryanodine receptor 1 (Ryr1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
