ROCK2
ROCK2，即Rho相關(guān)卷曲螺旋激酶2，別名Rho激酶2。它是一種絲氨酸/蘇氨酸蛋白激酶，分子量大約160 kD，屬于Rho/ROCK信號通路的關(guān)鍵組成部分。ROCK2的作用機(jī)制主要通過磷酸化多種底物蛋白，參與細(xì)胞形態(tài)、運(yùn)動(dòng)、增殖和凋亡等生理過程的調(diào)控。ROCK2在肌肉收縮、細(xì)胞形態(tài)和遷移、細(xì)胞增殖和分化以及細(xì)胞凋亡等方面發(fā)揮重要作用。此外，ROCK2與多種疾病的發(fā)生發(fā)展有關(guān)，包括糖尿病腎病、腫瘤、高血壓、神經(jīng)損傷性疾病等，因此作為藥物研發(fā)的靶點(diǎn)受到了廣泛關(guān)注。
熱銷產(chǎn)品
ROCK2 Recombinant Monoclonal Antibody (CSB-RA152329A0HU)
驗(yàn)證數(shù)據(jù)
Western Blot
Positive WB detected in: Hela whole cell lysate, MCF-7 whole cell lysate, L02 whole cell lysate, HepG2 whole cell lysate, Mouse Brain whole cell lysate, Rat Brain whole cell lysate
All lanes: ROCK2 antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 161 kDa
Observed band size: 161 kDa
Immunofluorescence staining of Hela Cells with CSB-RA152329A0HU at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeated by 0.2% TritonX-100, and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4℃. Nuclear DNA was labeled in blue with DAPI. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L).
Human Rho-associated coiled-coil containing protein kinase 2(Rock-2) ELISA Kit (CSB-E14993h)
驗(yàn)證數(shù)據(jù)
貨號：CSB-E14993h
規(guī)格：96T/48T
靈敏度：7.8 pg/mL
檢測范圍：0.625 ng/mL-40 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
ROCK2 Antibodies
ROCK2 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA020059GA01HU | ROCK2 Antibody | Human,Mouse,Rat | ELISA,WB,IF |
| CSB-PA035451 | Phospho-ROCK2 (Tyr722) Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA020059ESR1HU | ROCK2 Antibody | Human, Rat | ELISA, WB, IHC, IF |
| CSB-PA004018 | ROCK2 Antibody | Human,Mouse,Rat,Monkey | WB, ELISA |
| CSB-PA005112 | ROCK2 Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA242246 | ROCK2 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA081497 | ROCK2 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA020059DA01HU | ROCK2 Antibody | Human, Mouse | ELISA, WB |
| CSB-PA020059DB01HU | ROCK2 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA020059DC01HU | ROCK2 Antibody, FITC conjugated | Human | |
| CSB-PA020059DD01HU | ROCK2 Antibody, Biotin conjugated | Human | ELISA |
| CSB-RA152329A0HU | ROCK2 Recombinant Monoclonal Antibody | Human, Mouse, Rat | ELISA, WB, IF |
ROCK2 Proteins
ROCK2 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP020059MO CSB-EP020059MO CSB-BP020059MO CSB-MP020059MO CSB-EP020059MO-B |
Recombinant Mouse Rho-associated protein kinase 2 (Rock2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ROCK2 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP020059HU CSB-EP020059HU CSB-BP020059HU CSB-MP020059HU CSB-EP020059HU-B |
Recombinant Human Rho-associated protein kinase 2 (ROCK2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ROCK2 Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP636705BO CSB-EP636705BO CSB-BP636705BO CSB-MP636705BO CSB-EP636705BO-B |
Recombinant Bovine Rho-associated protein kinase 2 (ROCK2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ROCK2 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP720322RA CSB-EP720322RA CSB-BP720322RA CSB-MP720322RA CSB-EP720322RA-B |
Recombinant Rat Rho-associated protein kinase 2 (Rock2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ROCK2 ELISA Kit
ROCK2 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E14993h | Human Rho-associated coiled-coil containing protein kinase 2(Rock-2) ELISA Kit | serum, plasma, cell culture supernates | 7.8 pg/mL |
