ROCK1
ROCK1，即Rho相關(guān)卷曲螺旋激酶1，別名Rho激酶1、ROK-β、p160-ROCK。它是一種由ROCK1基因編碼的絲氨酸/蘇氨酸蛋白激酶，屬于Rho/ROCK信號通路的關(guān)鍵組成部分。ROCK1的作用機(jī)制主要是通過磷酸化多種底物蛋白，如肌球蛋白輕鏈、LIM激酶等，參與調(diào)節(jié)細(xì)胞形態(tài)、運動、收縮和增殖等生理過程。ROCK1在調(diào)控細(xì)胞骨架重組、細(xì)胞遷移、血管內(nèi)皮通透性以及組織收縮和生長等多種生理功能中發(fā)揮重要作用。此外，ROCK1的功能異常與糖尿病腎病、眼疾病、腫瘤、心臟病、神經(jīng)損傷性疾病、高血壓等多種疾病的發(fā)生發(fā)展有關(guān)，是藥物研發(fā)中的潛在靶點。
熱銷產(chǎn)品
驗證數(shù)據(jù)
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA057038(ROCK1 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using CSB-PA057038(ROCK1 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
ROCK1 Antibodies
ROCK1 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA020058GA01HU | ROCK1 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA004017 | ROCK1 Antibody | Human,Mouse,Rat,Monkey | WB, IHC, ELISA |
| CSB-PA040230 | ROCK1 Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA057038 | ROCK1 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA679461 | ROCK1 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA614415HA01HU | ROCK1 Antibody | Human | ELISA, WB, IHC, IF |
| CSB-PA614415HB01HU | ROCK1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA614415HC01HU | ROCK1 Antibody, FITC conjugated | Human | |
| CSB-PA614415HD01HU | ROCK1 Antibody, Biotin conjugated | Human | ELISA |
ROCK1 Proteins
ROCK1 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP020058MO CSB-EP020058MO CSB-BP020058MO CSB-MP020058MO CSB-EP020058MO-B |
Recombinant Mouse Rho-associated protein kinase 1 (Rock1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ROCK1 Proteins for Oryctolagus cuniculus (Rabbit)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP020058RB CSB-EP020058RB CSB-BP020058RB CSB-MP020058RB CSB-EP020058RB-B |
Recombinant Rabbit Rho-associated protein kinase 1 (ROCK1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ROCK1 Proteins for Pan troglodytes (Chimpanzee)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP020058EQV CSB-EP020058EQV CSB-BP020058EQV CSB-MP020058EQV CSB-EP020058EQV-B |
Recombinant Pan troglodytes Rho-associated protein kinase 1 (ROCK1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ROCK1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP614415HU CSB-EP614415HU CSB-BP614415HU CSB-MP614415HU CSB-EP614415HU-B |
Recombinant Human Rho-associated protein kinase 1 (ROCK1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ROCK1 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP717402RA CSB-EP717402RA CSB-BP717402RA CSB-MP717402RA CSB-EP717402RA-B |
Recombinant Rat Rho-associated protein kinase 1 (Rock1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ROCK1 Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP847572BO CSB-EP847572BO CSB-BP847572BO CSB-MP847572BO CSB-EP847572BO-B |
Recombinant Bovine Rho-associated protein kinase 1 (ROCK1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
