RET
RET是受體酪氨酸激酶家族的一員，其結(jié)構(gòu)包含細(xì)胞外域、跨膜域、酪氨酸激酶域和羧基末端。RET通過與特定配體結(jié)合，激活其胞內(nèi)區(qū)的酪氨酸激酶活性，進(jìn)而啟動下游信號轉(zhuǎn)導(dǎo)通路，影響細(xì)胞的生長、增殖、分化和凋亡等生物學(xué)過程。RET在維持多種細(xì)胞類型如神經(jīng)細(xì)胞、內(nèi)分泌細(xì)胞和腎臟細(xì)胞的正常功能中發(fā)揮著重要作用。然而，當(dāng)RET基因發(fā)生突變或異常表達(dá)時，可能導(dǎo)致疾病的發(fā)生，如甲狀腺髓樣癌等。因此，對RET的結(jié)構(gòu)、功能和生物學(xué)作用的研究不僅有助于我們理解其在正常生理過程中的作用，也為相關(guān)疾病的預(yù)防和治療提供了新的視角和策略。
熱銷產(chǎn)品
RET Recombinant Monoclonal Antibody (CSB-RA288083A0HU)
驗證數(shù)據(jù)
Overlay histogram showing Hela cells stained with CSB-RA288083A0HU (red line) at 1:50. The cells were fixed in 4% formaldehyde (15min) and permeated by 0.2% TritonX-100 for 10min. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1ug/1*106cells) for 45min at 4℃.The secondary antibody used was FITC-conjugated goat anti-rabbit IgG (H+L) at 1/200 dilution for 30min at 4℃. Control antibody (green line) was Rabbit IgG (1μg/1*106 cells) used under the same conditions. Acquisition of >10,000 events was performed.
RET Antibodies
RET for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA019572DSR1HU | RET Antibody | Human | ELISA, WB, IHC |
| CSB-PA019572DSR2HU | RET Antibody | Human | ELISA, IHC |
| CSB-PA003961 | RET Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA003963 | RET Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA040202 | Phospho-RET (Y1015) Antibody | Human,Mouse,Rat,Monkey | WB, ELISA |
| CSB-PA040203 | Phospho-RET (Y1062) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA040204 | Phospho-RET (Y905) Antibody | Human,Mouse,Rat | IHC, IF, ELISA |
| CSB-RA288083A0HU | RET Recombinant Monoclonal Antibody | Human | ELISA, FC |
RET Proteins
RET Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP019572HU CSB-EP019572HU CSB-BP019572HU CSB-MP019572HU CSB-EP019572HU-B |
Recombinant Human Proto-oncogene tyrosine-protein kinase receptor Ret (RET), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
