RB1
Retinoblastoma-associated protein is a protein in humans that is encoded by RB1 gene. Key regulator of entry into cell division that acts as a tumor suppressor. Promotes G0-G1 transition when phosphorylated by CDK3/cyclin-C. Acts as a transcription repressor of E2F1 target genes. The underphosphorylated, active form of RB1 interacts with E2F1 and represses its transcription activity, leading to cell cycle arrest. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV39H1, KMT5B and KMT5C, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Inhibits the intrinsic kinase activity of TAF1.
RB1 Antibodies
RB1 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA019386GA01HU | RB1 Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA201739 | Phospho-RB1 (Ser795) Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
| CSB-PA193785 | Phospho-RB1 (Ser807) Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA133410 | Phospho-RB1 (Ser780) Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
| CSB-PA990932 | RB1 (Ab-795) Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA445358 | RB1 (Ab-807) Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA095986 | RB1 (Ab-780) Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA582717 | Phospho-RB1 (Ser608) Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA036254 | RB1 (Ab-608) Antibody | Human,Mouse | ELISA,WB |
| CSB-PA237047 | Phospho-RB1 (Thr826) Antibody | Human,Mouse,Rat | ELISA,WB,IF |
| CSB-PA019386ESR2HU | RB1 Antibody | Human | ELISA, IHC |
| CSB-PA000616 | Phospho-RB1 (S780) Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA000617 | Phospho-RB1 (S807) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA003947 | RB1 Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA003948 | RB1 Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA040164 | Phospho-RB1 (S795) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA040165 | Phospho-RB1 (S811) Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA040166 | Phospho-RB1 (T826) Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA040167 | Phospho-RB1 (S608) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA040168 | Phospho-RB1 (S612) Antibody | Human | IHC, ELISA |
| CSB-PA040169 | Phospho-RB1 (S788) Antibody | Human,Mouse,Rat | IHC, ELISA |
| CSB-PA040170 | Phospho-RB1 (T821) Antibody | Human,Mouse,Rat | IHC, IF, ELISA |
| CSB-PA040171 | Phospho-RB1 (S249) Antibody | Human,Mouse,Rat | IF, ELISA |
| CSB-PA040172 | RB1 Antibody | Human,Mouse,Rat | IHC, IF, ELISA |
| CSB-PA040173 | RB1 Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA040174 | RB1 Antibody | Human,Mouse,Rat | IHC, IF, ELISA |
| CSB-PA040176 | RB1 Antibody | Human,Mouse,Rat | IHC, IF, ELISA |
| CSB-PA040177 | RB1 Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA232358 | RB1 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-RA019386A807phHU | Phospho-RB1 (S807) Recombinant Monoclonal Antibody | Human | ELISA, IF |
| CSB-RA019386A780phHU | Phospho-RB1 (S780) Recombinant Monoclonal Antibody | Human | ELISA, IHC, IF, IP |
RB1 Proteins
RB1 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP019386MO CSB-EP019386MO CSB-BP019386MO CSB-MP019386MO CSB-EP019386MO-B |
Recombinant Mouse Retinoblastoma-associated protein (Rb1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
RB1 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP019386RA CSB-EP019386RA CSB-BP019386RA CSB-MP019386RA CSB-EP019386RA-B |
Recombinant Rat Retinoblastoma-associated protein (Rb1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-RP155294r(A3) | Recombinant Rat Retinoblastoma-associated protein (Rb1), partial | E.coli |
RB1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP019386HU CSB-BP019386HU CSB-MP019386HU CSB-EP019386HU-B |
Recombinant Human Retinoblastoma-associated protein (RB1), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP019386HU2 | Recombinant Human Retinoblastoma-associated protein (RB1), partial | E.coli |
| CSB-EP019386HU | Recombinant Human Retinoblastoma-associated protein (RB1), partial | E.coli |
RB1 Proteins for Cocos nucifera (Coconut)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP814119CMW CSB-EP814119CMW CSB-BP814119CMW CSB-MP814119CMW CSB-EP814119CMW-B |
Recombinant Cocos nucifera Retinoblastoma-related protein (Rb1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
RB1 Proteins for Gallus gallus (Chicken)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP856183CH CSB-EP856183CH CSB-BP856183CH CSB-MP856183CH CSB-EP856183CH-B |
Recombinant Chicken Retinoblastoma-associated protein (RB1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
RB1 Proteins for Nicotiana tabacum (Common tobacco)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP871200NHE CSB-EP871200NHE CSB-BP871200NHE CSB-MP871200NHE CSB-EP871200NHE-B |
Recombinant Nicotiana tabacum Retinoblastoma-related protein 1 (RB1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
