PTH1R

PTH1R，全稱為甲狀旁腺激素1型受體，也被稱為PTH/PTHrP受體或PTH1受體。該蛋白在骨骼發育和穩態中扮演重要角色，主要由甲狀旁腺激素（PTH）和甲狀旁腺激素相關肽（PTHrP）激活。PTH1R主要在成骨細胞中表達，通過調節骨代謝影響骨骼健康。與PTH1R相關的疾病包括骨質疏松癥和腎臟疾病。近年來，針對PTH1R的藥物研發取得了顯著進展，新型小分子激動劑藥物的開發為治療相關疾病提供了新的方向。

熱銷產品

Recombinant Human Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH1R), partial (Active) (CSB-MP018988HU)

驗證數據

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Activity
Measured by its binding ability in a functional ELISA. Immobilized Human PTH1R at 2 μg/ml can bind Anti-PTH1R recombinant antibody (CSB-RA018988MA1HU). The EC₅₀ is 0.7813-1.048 ng/mL.

PTH1R Recombinant Monoclonal Antibody (CSB-RA018988MA1HU) captured on Protein A Chip can bind Recombinant Human PTH1R protein with an affinity constant of 0.14 nM as detected by MetaSPR Assay (WeSPRTM 200).

PTH1R Recombinant Monoclonal Antibody (CSB-RA018988MA1HU)

驗證數據

The Binding Activity of Human PTH1R with Anti-PTH1R recombinant antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human PTH1R(CSB-MP018988HU) at 2 μg/mL can bind Anti-PTH1R recombinant antibody. The EC₅₀ is 0.7813-1.048 ng/mL.

The Binding Activity of Rat Pth1r with Anti-PTH1R recombinant antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Rat Pth1r（CSB-MP018988RA2） at 2 μg/mL can bind Anti-PTH1R recombinant antibody. The EC₅₀ is 0.7384-1.203 ng/mL.

The Binding Activity of Macaca fascicularit PTH1R with Anti-PTH1R recombinant antibody
Activity: Measured by its binding ability in a functional ELISA.Immobilized Macaca fascicularit PTH1R(CSB-MP018988MOV4) at 2 μg/mL can bind Anti-PTH1R recombinant antibody. The EC₅₀ is 1.072 to 1.403 ng/mL.

PTH1R Antibody

PTH1R Protein

PTH1R Antibodies

PTH1R for Homo sapiens (Human)

產品貨號	產品名稱	種屬反應性	應用類型
CSB-PA040068	PTH1R Antibody	Human,Mouse,Rat	WB, IHC, IF, ELISA
CSB-PA440946	PTH1R Antibody	Human	WB, IHC, ELISA
CSB-PA018988LA01HU	PTH1R Antibody	Human, Rat, Mouse	ELISA, WB
CSB-PA018988LB01HU	PTH1R Antibody, HRP conjugated	Human	ELISA
CSB-PA018988LC01HU	PTH1R Antibody, FITC conjugated	Human
CSB-PA018988LD01HU	PTH1R Antibody, Biotin conjugated	Human	ELISA
CSB-RA162005A0HU	PTH1R Recombinant Monoclonal Antibody	Human	ELISA, WB
CSB-RA018988MA1HU	PTH1R Recombinant Monoclonal Antibody	Human, Rat, Macaca fascicularis	ELISA

PTH1R Proteins

PTH1R Proteins for Rattus norvegicus (Rat)

產品貨號	產品名稱	來源
CSB-YP018988RA1 CSB-EP018988RA1 CSB-BP018988RA1 CSB-MP018988RA1 CSB-EP018988RA1-B	Recombinant Rat Parathyroid hormone/parathyroid hormone-related peptide receptor (Pth1r), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF018988RA	Recombinant Rat Parathyroid hormone/parathyroid hormone-related peptide receptor (Pth1r)	in vitro E.coli expression system

PTH1R Proteins for Mus musculus (Mouse)

產品貨號	產品名稱	來源
CSB-YP018988MO1 CSB-EP018988MO1 CSB-BP018988MO1 CSB-MP018988MO1 CSB-EP018988MO1-B	Recombinant Mouse Parathyroid hormone/parathyroid hormone-related peptide receptor (Pth1r), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF018988MO	Recombinant Mouse Parathyroid hormone/parathyroid hormone-related peptide receptor (Pth1r)	in vitro E.coli expression system

PTH1R Proteins for Sus scrofa (Pig)

產品貨號	產品名稱	來源
CSB-YP018988PI CSB-EP018988PI CSB-BP018988PI CSB-EP018988PI-B	Recombinant Pig Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH1R), partial	Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli
CSB-MP018987PI	Recombinant Pig Parathyroid hormone (PTH)	Mammalian cell
CSB-CF018988PI	Recombinant Pig Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH1R)	in vitro E.coli expression system

PTH1R Proteins for Didelphis marsupialis virginiana (North American opossum)

產品貨號	產品名稱	來源
CSB-YP018988DKL1 CSB-EP018988DKL1 CSB-BP018988DKL1 CSB-MP018988DKL1 CSB-EP018988DKL1-B	Recombinant Didelphis marsupialis virginiana Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH1R), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF018988DKL	Recombinant Didelphis marsupialis virginiana Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH1R)	in vitro E.coli expression system

PTH1R Proteins for Bos taurus (Bovine)

產品貨號	產品名稱	來源
CSB-YP630854BO1 CSB-EP630854BO1 CSB-BP630854BO1 CSB-MP630854BO1 CSB-EP630854BO1-B	Recombinant Bovine Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH1R), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF630854BO	Recombinant Bovine Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH1R)	in vitro E.coli expression system

PTH1R Proteins for Pongo abelii (Sumatran orangutan)

產品貨號	產品名稱	來源
CSB-YP732722PYX1 CSB-EP732722PYX1 CSB-BP732722PYX1 CSB-MP732722PYX1 CSB-EP732722PYX1-B	Recombinant Pongo abelii Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH1R), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF732722PYX	Recombinant Pongo abelii Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH1R)	in vitro E.coli expression system

PTH1R Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

產品貨號	產品名稱	來源
CSB-YP866142DO1 CSB-EP866142DO1 CSB-BP866142DO1 CSB-MP866142DO1 CSB-EP866142DO1-B	Recombinant Dog Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH1R), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli