PTGS2
PTGS2，即前列腺素內過氧化物合酶2，也被稱為環氧化酶2（Cyclooxygenase-2，COX-2）。它是一種在多種細胞類型中表達的酶，尤其在炎癥和組織損傷時表達水平上升。PTGS2的作用機制是通過催化花生四烯酸轉化為前列腺素H2，進而參與多種生理和病理過程，包括炎癥反應、疼痛感知、發熱以及血小板聚集等。PTGS2激活的信號通路涉及NMDA受體依賴的神經遞質釋放、細胞增殖和細胞存活等。在生物學意義上，PTGS2不僅在維持正常生理功能中發揮作用，而且在腫瘤發展、神經損傷和炎癥性疾病中具有重要作用。其異常表達與多種疾病包括癌癥、神經退行性疾病和心血管疾病等有關，是許多病理過程中的關鍵調控點。
熱銷產品
Recombinant Human Prostaglandin G/H synthase 2 (PTGS2), partial (CSB-EP018986HU)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP018986HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) PTGS2.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP018986HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) PTGS2.
PTGS2 Recombinant Monoclonal Antibody (CSB-RA920283A0HU)
驗證數據
Western Blot
Positive WB detected in: U-87 whole cell lysate
All lanes: COX2 Antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 69 kDa
Observed band size: 69 kDa
Immunofluorescence staining of HepG2 Cells with CSB-RA920283A0HU at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeated by 0.2% TritonX-100, and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4℃. Nuclear DNA was labeled in blue with DAPI. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L).
PTGS2 Antibodies
PTGS2 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA015073GA01HU | PTGS2 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA018986GA01HU | PTGS2 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA997318 | PTGS2 Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
| CSB-PA000361 | PTGS2 Antibody | Human | WB |
| CSB-PA001764 | PTGS2 Antibody | Human | WB, IHC, IF, ELISA |
| CSB-PA217397 | PTGS2 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA184426 | PTGS2 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-RA018986A0HU | PTGS2 Recombinant Monoclonal Antibody | Human | ELISA |
| CSB-PA018986LA01HU | PTGS2 Antibody | Human | ELISA, WB |
| CSB-PA018986LB01HU | PTGS2 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA018986LC01HU | PTGS2 Antibody, FITC conjugated | Human | |
| CSB-PA018986LD01HU | PTGS2 Antibody, Biotin conjugated | Human | ELISA |
| CSB-RA920283A0HU | PTGS2 Recombinant Monoclonal Antibody | Human | ELISA, WB, IF |
PTGS2 for H, M, R
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-MA000320 | PTGS2 Monoclonal Antibody | Human,Mouse,Rat | ELISA,IHC |
PTGS2 Proteins
PTGS2 Proteins for Ovis aries (Sheep)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP018986SH CSB-EP018986SH CSB-BP018986SH CSB-MP018986SH CSB-EP018986SH-B |
Recombinant Sheep Prostaglandin G/H synthase 2 (PTGS2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PTGS2 Proteins for Cavia porcellus (Guinea pig)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP018986GU CSB-EP018986GU CSB-BP018986GU CSB-MP018986GU CSB-EP018986GU-B |
Recombinant Guinea pig Prostaglandin G/H synthase 2 (PTGS2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PTGS2 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP018986HU CSB-BP018986HU CSB-MP018986HU CSB-EP018986HU-B |
Recombinant Human Prostaglandin G/H synthase 2 (PTGS2), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP018986HU | Recombinant Human Prostaglandin G/H synthase 2 (PTGS2), partial | E.coli |
PTGS2 Proteins for Gallus gallus (Chicken)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP018986CH CSB-EP018986CH CSB-BP018986CH CSB-MP018986CH CSB-EP018986CH-B |
Recombinant Chicken Prostaglandin G/H synthase 2 (PTGS2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PTGS2 Proteins for Oryctolagus cuniculus (Rabbit)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP018986RB CSB-EP018986RB CSB-BP018986RB CSB-MP018986RB CSB-EP018986RB-B |
Recombinant Rabbit Prostaglandin G/H synthase 2 (PTGS2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PTGS2 Proteins for Equus caballus (Horse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP018986HO CSB-EP018986HO CSB-BP018986HO CSB-MP018986HO CSB-EP018986HO-B |
Recombinant Horse Prostaglandin G/H synthase 2 (PTGS2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PTGS2 Proteins for Bos taurus (Bovine)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP018986BO CSB-EP018986BO CSB-BP018986BO CSB-MP018986BO CSB-EP018986BO-B |
Recombinant Bovine Prostaglandin G/H synthase 2 (PTGS2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PTGS2 Proteins for Mustela vison (American mink) (Neovison vison)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP018986MVE CSB-EP018986MVE CSB-BP018986MVE CSB-MP018986MVE CSB-EP018986MVE-B |
Recombinant Mustela vison Prostaglandin G/H synthase 2 (PTGS2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PTGS2 Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP018986RA CSB-EP018986RA CSB-BP018986RA CSB-MP018986RA CSB-EP018986RA-B |
Recombinant Rat Prostaglandin G/H synthase 2 (Ptgs2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PTGS2 ELISA Kit
PTGS2 ELISA Kit for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E10103h | Human cyclooxygenase-2,COX-2 ELISA Kit | serum, plasma, tissue homogenates, cell lysates | 0.31 ng/mL |
PTGS2 ELISA Kit for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E12910m | Mouse cyclooxygenase-2,COX-2 ELISA Kit | serum, plasma, tissue homogenates, cell lysates | 7.8 pg/mL |
PTGS2 ELISA Kit for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E13399r | Rat cyclooxygenase-2,COX-2 ELISA Kit | serum, plasma, tissue homogenates | 0.39 ng/mL |
