PRMT7
PRMT7，即蛋白質(zhì)精氨酸甲基轉(zhuǎn)移酶7，別名ANM7、FLJ10640、KIAA1933。PRMT7是蛋白質(zhì)精氨酸N-甲基轉(zhuǎn)移酶家族的一員，其編碼的酶將單個(gè)甲基基團(tuán)轉(zhuǎn)移到精氨酸殘基上，生成組蛋白及其他蛋白質(zhì)底物上的單甲基精氨酸。PRMT7可對(duì)底物蛋白進(jìn)行翻譯后甲基化修飾，參與染色質(zhì)結(jié)構(gòu)調(diào)控、基因表達(dá)、細(xì)胞信號(hào)轉(zhuǎn)導(dǎo)、蛋白質(zhì)剪接體組裝、細(xì)胞遷移、抗藥性、再生能力及多能性維持等細(xì)胞活動(dòng)。PRMT7在多種生理和病理過程中起關(guān)鍵作用，包括神經(jīng)元分化、雄性生殖系印記、小核核糖核蛋白生物發(fā)生及Wnt信號(hào)通路調(diào)控。PRMT7的異常表達(dá)或功能失調(diào)與多種疾病相關(guān)，包括智力障礙、矮小及其他綜合征。
熱銷產(chǎn)品
PRMT7 Antibody (CSB-PA885738LA01HU)
驗(yàn)證數(shù)據(jù)
Western Blot
Positive WB detected in: Mouse spleen tissue, Mouse lung tissue, Mouse kidney tissue, Mouse brain tissue
All lanes: PRMT7 antibody at 6.2μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 79, 63, 74, 64 kDa
Observed band size: 79 kDa
Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA885738LA01HU at dilution of 1:100
Immunofluorescent analysis of Hela cells using CSB-PA885738LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
PRMT7 Antibodies
PRMT7 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA036451 | PRMT7 Antibody | Human | ELISA,WB |
| CSB-PA559119 | PRMT7 Antibody | Human | ELISA,WB |
| CSB-PA885738LA01HU | PRMT7 Antibody | Human, Mouse | ELISA, WB, IHC, IF |
PRMT7 Proteins
PRMT7 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP885738HU CSB-EP885738HU CSB-BP885738HU CSB-MP885738HU CSB-EP885738HU-B |
Recombinant Human Protein arginine N-methyltransferase 7 (PRMT7) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
