PRKDC
DNA-dependent protein kinase catalytic subunit is a protein in humans that is encoded by PRKDC gene. Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. Must be bound to DNA to express its catalytic properties. Promotes processing of hairpin DNA structures in V(D)J recombination by activation of the hairpin endonuclease artemis (DCLRE1C). The assembly of the DNA-PK complex at DNA ends is also required for the NHEJ ligation step. Required to protect and align broken ends of DNA. May also act as a scaffold protein to aid the localization of DNA repair proteins to the site of damage.
PRKDC Antibodies
PRKDC for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA018714GA01HU | PRKDC Antibody | Human,Mouse | ELISA,WB |
| CSB-PA909958 | Phospho-PRKDC (Thr2609) Antibody | Human | ELISA,WB |
| CSB-PA178115 | PRKDC (Ab-2609) Antibody | Human | ELISA,WB |
| CSB-PA572497 | PRKDC Antibody | Human,Mouse | ELISA,WB,IHC,IF |
| CSB-PA002177 | PRKDC Antibody | Human,Mouse | WB, IHC, IF, ELISA |
| CSB-PA030277 | Phospho-PRKDC (S2612) Antibody | Human | IHC, ELISA |
| CSB-PA030278 | Phospho-PRKDC (S2056) Antibody | Human,Mouse | IHC, ELISA |
| CSB-PA030279 | Phospho-PRKDC (T2647) Antibody | Human | IHC, IF, ELISA |
| CSB-PA030280 | Phospho-PRKDC (T2638) Antibody | Human,Mouse | IF, ELISA |
| CSB-PA030281 | PRKDC Antibody | Human | IF, ELISA |
| CSB-PA030282 | PRKDC Antibody | Human | IF, ELISA |
| CSB-PA030283 | PRKDC Antibody | Human,Mouse | IF, ELISA |
| CSB-PA030284 | PRKDC Antibody | Human | IHC, ELISA |
| CSB-PA030285 | PRKDC Antibody | Human,Mouse | IHC, ELISA |
| CSB-PA018714LA01HU | PRKDC Antibody | Human | ELISA, WB |
| CSB-PA018714LD01HU | PRKDC Antibody, Biotin conjugated | Human | ELISA |
| CSB-RA018714A2056phHU | Phospho-PRKDC (S2056) Recombinant Monoclonal Antibody | Human | ELISA, IF |
PRKDC Proteins
PRKDC Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP018714HU CSB-EP018714HU CSB-BP018714HU CSB-MP018714HU CSB-EP018714HU-B |
Recombinant Human DNA-dependent protein kinase catalytic subunit (PRKDC), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRKDC Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP018714MO CSB-BP018714MO CSB-MP018714MO CSB-EP018714MO-B |
Recombinant Mouse DNA-dependent protein kinase catalytic subunit (Prkdc), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP018714MO | Recombinant Mouse DNA-dependent protein kinase catalytic subunit (Prkdc), partial | E.coli |
PRKDC Proteins for Gallus gallus (Chicken)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP823129CH CSB-EP823129CH CSB-BP823129CH CSB-MP823129CH CSB-EP823129CH-B |
Recombinant Chicken DNA-dependent protein kinase catalytic subunit (PRKDC), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRKDC Proteins for Canis familiaris (Dog) (Canis lupus familiaris)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP851944DO CSB-EP851944DO CSB-BP851944DO CSB-MP851944DO CSB-EP851944DO-B |
Recombinant Dog DNA-dependent protein kinase catalytic subunit (PRKDC), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRKDC Proteins for Xenopus laevis (African clawed frog)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP872070XBE CSB-EP872070XBE CSB-BP872070XBE CSB-MP872070XBE CSB-EP872070XBE-B |
Recombinant Xenopus laevis DNA-dependent protein kinase catalytic subunit (prkdc), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
