PRKCI
Protein kinase C iota type is a protein in humans that is encoded by PRKCI gene. Calcium- and diacylglycerol-independent serine/ threonine-protein kinase that plays a general protective role against apoptotic stimuli, is involved in NF-kappa-B activation, cell survival, differentiation and polarity, and contributes to the regulation of microtubule dynamics in the early secretory pathway. Is necessary for BCR-ABL oncogene-mediated resistance to apoptotic drug in leukemia cells, protecting leukemia cells against drug-induced apoptosis. In cultured neurons, prevents amyloid beta protein-induced apoptosis by interrupting cell death process at a very early step. In glioblastoma cells, may function downstream of phosphatidylinositol 3-kinase (PI(3)K) and PDPK1 in the promotion of cell survival by phosphorylating and inhibiting the pro-apoptotic factor BAD.
PRKCI Antibodies
PRKCI for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA018707GA01HU | PRKCI Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
PRKCI Proteins
PRKCI Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP018707HU CSB-EP018707HU CSB-BP018707HU CSB-MP018707HU CSB-EP018707HU-B |
Recombinant Human Protein kinase C iota type (PRKCI) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRKCI Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP018707RA CSB-EP018707RA CSB-BP018707RA CSB-MP018707RA CSB-EP018707RA-B |
Recombinant Rat Protein kinase C iota type (Prkci) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRKCI Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP714008MO CSB-EP714008MO CSB-BP714008MO CSB-MP714008MO CSB-EP714008MO-B |
Recombinant Mouse Protein kinase C iota type (Prkci) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRKCI Proteins for Pongo abelii (Sumatran orangutan)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP735654PYX CSB-EP735654PYX CSB-BP735654PYX CSB-MP735654PYX CSB-EP735654PYX-B |
Recombinant Pongo abelii Protein kinase C iota type (PRKCI), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRKCI Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP845883DIL CSB-EP845883DIL CSB-BP845883DIL CSB-MP845883DIL CSB-EP845883DIL-B |
Recombinant Danio rerio Protein kinase C iota type (prkci), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
