PRKCH
Protein kinase C eta type is a protein in humans that is encoded by PRKCH gene. Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells. In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentiation. Associates with the cyclin CCNE1-CDK2-CDKN1B complex and inhibits CDK2 kinase activity, leading to RB1 dephosphorylation and thereby G1 arrest in keratinocytes.
PRKCH Antibodies
PRKCH for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA15879A0Rb | PRKCH Antibody | Human, Mouse, Rat | ELISA, WB, IHC |
| CSB-PA15879B0Rb | PRKCH Antibody, HRP conjugated | Human | ELISA |
| CSB-PA15879C0Rb | PRKCH Antibody, FITC conjugated | Human | |
| CSB-PA15879D0Rb | PRKCH Antibody, Biotin conjugated | Human | ELISA |
PRKCH Proteins
PRKCH Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP018706HU CSB-BP018706HU CSB-MP018706HU CSB-EP018706HU-B |
Recombinant Human Protein kinase C eta type (PRKCH) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP018706HU | Recombinant Human Protein kinase C eta type (PRKCH) | E.coli |
| CSB-EP018706HUa0 | Recombinant Human Protein kinase C eta type (PRKCH) | E.coli |
PRKCH Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP018706MO CSB-EP018706MO CSB-BP018706MO CSB-MP018706MO CSB-EP018706MO-B |
Recombinant Mouse Protein kinase C eta type (Prkch) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRKCH Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP723752RA CSB-EP723752RA CSB-BP723752RA CSB-MP723752RA CSB-EP723752RA-B |
Recombinant Rat Protein kinase C eta type (Prkch) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
