PDK2
[Pyruvate dehydrogenase is a protein in humans that is encoded by PDK2 gene. Kinase that plays a key role in the regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate. Inhibition of pyruvate dehydrogenase decreases glucose utilization and increases fat metabolism. Mediates cellular responses to insulin. Plays an important role in maintaining normal blood glucose levels and in metabolic adaptation to nutrient availability. Via its regulation of pyruvate dehydrogenase activity, plays an important role in maintaining normal blood pH and in preventing the accumulation of ketone bodies under starvation. Plays a role in the regulation of cell proliferation and in resistance to apoptosis under oxidative stress. Plays a role in p53/TP53-mediated apoptosis.
PDK2 Antibodies
PDK2 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA017728GA01HU | PDK2 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA574849 | PDK2 Antibody | Human,Mouse | ELISA,WB |
| CSB-PA618976ESR2HU | PDK2 Antibody | Human, Mouse | ELISA, WB, IHC |
| CSB-PA003732 | PDK2 Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA656448 | PDK2 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA266329 | PDK2 Antibody | Human,Mouse,Rat | ELISA,WB |
PDK2 Proteins
PDK2 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP618976HU CSB-EP618976HU CSB-BP618976HU CSB-MP618976HU CSB-EP618976HU-B |
Recombinant Human [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (PDK2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PDK2 Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP727335RA CSB-EP727335RA CSB-BP727335RA CSB-MP727335RA CSB-EP727335RA-B |
Recombinant Rat [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial (Pdk2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PDK2 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP867508MO CSB-EP867508MO CSB-BP867508MO CSB-MP867508MO CSB-EP867508MO-B |
Recombinant Mouse [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial (Pdk2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
