PAX6

PAX6，即配對框基因6，是一種在進(jìn)化上高度保守的轉(zhuǎn)錄因子，由PAX6基因編碼。它在眼睛、大腦、鼻子和胰腺等器官的發(fā)育中起著至關(guān)重要的作用。PAX6通過結(jié)合特定的DNA序列，調(diào)控下游基因的表達(dá)，從而參與多種生物學(xué)過程，包括胚胎發(fā)育和器官形成。PAX6的功能異常與多種眼部疾病相關(guān)，如先天性白內(nèi)障、無虹膜和小眼球癥等。此外，PAX6還涉及到腫瘤發(fā)生等過程，其在腫瘤中的表達(dá)變化可能影響腫瘤細(xì)胞的增殖和分化。PAX6參與的信號通路包括但不限于MEK/ERK信號通路，該通路在肝星狀細(xì)胞的活化和增殖中發(fā)揮作用。總的來說，PAX6是一個多功能的調(diào)控分子，對維持生物體的正常發(fā)育和生理功能至關(guān)重要。

熱銷產(chǎn)品

Recombinant Human Paired box protein Pax-6 (PAX6) (CSB-EP017492HU)

驗證數(shù)據(jù)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

PAX6 Recombinant Monoclonal Antibody (CSB-RA577229A0HU)

驗證數(shù)據(jù)

IHC image of CSB-RA577229A0HU diluted at 1:100 and staining in paraffin-embedded human pancreati tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.55% DAB.

IHC image of CSB-RA577229A0HU diluted at 1:100 and staining in paraffin-embedded human glioma cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.55% DAB.

Overlay Peak curve showing SH-SY5Y cells stained with CSB-RA577229A0HU (red line) at 1:50. The cells were fixed in 4% formaldehyde and permeated by 0.2% TritonX-100. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1μg/1*10⁶cells) for 45min at 4℃. The secondary antibody used was FITC-conjugated Goat Anti-rabbit IgG(H+L) at 1:200 dilution for 35min at 4℃.Control antibody (green line) was rabbit IgG (1μg/1*10⁶cells) used under the same conditions. Acquisition of >10,000 events was performed.

Mouse paired box 6 (PAX6) ELISA kit (CSB-EL017492MO)

驗證數(shù)據(jù)

貨號：CSB-EL017492MO

規(guī)格：96T/48T

靈敏度：11.72 pg/mL

檢測范圍：46.88 pg/mL-3000 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

PAX6 Antibody

PAX6 Protein

PAX6 ELISA Kit

PAX6 Antibodies

PAX6 for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA017492GA01HU	PAX6 Antibody	Human,Mouse	ELISA,WB,IHC,IF
CSB-PA017492DSR1HU	PAX6 Antibody	Human	ELISA, IHC
CSB-PA017492DSR2HU	PAX6 Antibody	Human, Mouse	ELISA, WB, IHC
CSB-RA577229A0HU	PAX6 Recombinant Monoclonal Antibody	Human	ELISA, IHC, FC

PAX6 Proteins

PAX6 Proteins for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP017492HU CSB-BP017492HU CSB-MP017492HU CSB-EP017492HU-B	Recombinant Human Paired box protein Pax-6 (PAX6)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP017492HU	Recombinant Human Paired box protein Pax-6 (PAX6)	E.coli

PAX6 Proteins for Gallus gallus (Chicken)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP017492CH CSB-EP017492CH CSB-BP017492CH CSB-MP017492CH CSB-EP017492CH-B	Recombinant Chicken Paired box protein Pax-6 (PAX6)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PAX6 Proteins for Mus musculus (Mouse)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP017492MO CSB-EP017492MO CSB-BP017492MO CSB-MP017492MO CSB-EP017492MO-B	Recombinant Mouse Paired box protein Pax-6 (Pax6)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PAX6 Proteins for Rattus norvegicus (Rat)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP017492RA CSB-EP017492RA CSB-BP017492RA CSB-MP017492RA CSB-EP017492RA-B	Recombinant Rat Paired box protein Pax-6 (Pax6)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PAX6 Proteins for Coturnix coturnix japonica (Japanese quail) (Coturnix japonica)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP017492DXJ CSB-EP017492DXJ CSB-BP017492DXJ CSB-MP017492DXJ CSB-EP017492DXJ-B	Recombinant Coturnix coturnix japonica Paired box protein Pax-6 (PAX6)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PAX6 Proteins for Xenopus laevis (African clawed frog)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP017492XBE CSB-EP017492XBE CSB-BP017492XBE CSB-MP017492XBE CSB-EP017492XBE-B	Recombinant Xenopus laevis Paired box protein Pax-6 (pax6)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PAX6 Proteins for Oryzias latipes (Medaka fish) (Japanese ricefish)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP017492OFH CSB-EP017492OFH CSB-BP017492OFH CSB-MP017492OFH CSB-EP017492OFH-B	Recombinant Oryzias latipes Paired box protein Pax-6 (pax6)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PAX6 Proteins for Bos taurus (Bovine)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP635859BO CSB-EP635859BO CSB-BP635859BO CSB-MP635859BO CSB-EP635859BO-B	Recombinant Bovine Paired box protein Pax-6 (PAX6)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli