PAK2
PAK2，全稱為p21 (RAC1) activated kinase 2，是一種重要的蛋白酶激酶，在細胞信號傳導通路中扮演著關鍵角色。該蛋白屬于蛋白激酶Cdc42/Rac-activated kinase (PAK) 家族，與細胞運動、增殖等多種生物學過程密切相關。PAK2通過與Cdc42和Rac蛋白結合而被激活，參與細胞的遷移和測定。在細胞增殖方面，PAK2通過激活細胞周期相關基因和細胞核受體，促進細胞的增殖。此外，PAK2在細胞凋亡過程中也發揮著重要作用，可調控多種信號通路，對程序性細胞的調控至關重要。PAK2重組蛋白作為一種生物制藥產品，在生物學研究和醫學應用中具有廣闊的應用前景。
熱銷產品
PAK2 Recombinant Monoclonal Antibody (CSB-RA592787A0HU)
驗證數據
Western Blot
Positive WB detected in: 293 whole cell lysate, Jurkat whole cell lysate, Raji whole cell lysate, Mouse brain tissue, Rat brain tissue
All lanes: PAK2 antibody at 1:2000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 59 kDa
Observed band size: 59 kDa
Overlay histogram showing HepG2 cells stained with CSB-RA592787A0HU (red line) at 1:50. The cells were fixed with 70% Ethylalcohol (18h) and then incubated in 10% normal goat serum to block non-specific protein-protein interactions followedby the antibody (1μg/1*106 cells) for 1 h at 4℃.The secondary antibody used was FITC-conjugated goat anti-rabbit IgG (H+L) at 1/200 dilution for 30min at 4℃. Control antibody (green line) was Rabbit IgG (1μg/1*106 cells) used under the same conditions. Acquisition of >10,000 events was performed.
Immunoprecipitating PAK2 in Raji whole cell lysate
Lane 1: Rabbit control IgG instead of CSB-RA592787A0HU in Raji whole cell lysate.
For western blotting,a HRP-conjugated Protein G antibody was used as the secondary antibody (1/2000)
Lane 2: CSB-RA592787A0HU(2μg)+ Raji whole cell lysate(500μg)
Lane 3: Raji whole cell lysate (10μg)
PAK2 Antibodies
PAK2 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA017406GA01HU | PAK2 Antibody | Human | ELISA,WB,IHC,IF |
| CSB-PA622641DSR1HU | PAK2 Antibody | Human | ELISA, WB, IHC |
| CSB-PA149930 | Phospho-PAK2 (Ser197) Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA101227 | PAK2 (Ab-192) Antibody | Human,Mouse | ELISA,WB |
| CSB-PA827528 | PAK2 (Ab-197) Antibody | Human,Mouse | ELISA,WB |
| CSB-PA951578 | Phospho-PAK2 (Ser141) Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA020221 | Phospho-PAK2 (S192) Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA020222 | Phospho-PAK2 (S141) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA020226 | Phospho-PAK2 (S197) Antibody | Human,Mouse,Rat | IHC, ELISA |
| CSB-PA020229 | PAK2 Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA020230 | PAK2 Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA010536 | Phospho-PAK2 (S20) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA010537 | PAK2 Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA922459 | PAK2 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA552213 | PAK2 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-RA592787A0HU | PAK2 Recombinant Monoclonal Antibody | Human, Mouse, Rat | ELISA, WB, FC, IP |
PAK2 Proteins
PAK2 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP622641HU CSB-EP622641HU CSB-BP622641HU CSB-MP622641HU CSB-EP622641HU-B |
Recombinant Human Serine/threonine-protein kinase PAK 2 (PAK2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PAK2 Proteins for Oryctolagus cuniculus (Rabbit)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP641838RB CSB-EP641838RB CSB-BP641838RB CSB-MP641838RB CSB-EP641838RB-B |
Recombinant Rabbit Serine/threonine-protein kinase PAK 2 (PAK2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PAK2 Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP727060RA CSB-EP727060RA CSB-BP727060RA CSB-MP727060RA CSB-EP727060RA-B |
Recombinant Rat Serine/threonine-protein kinase PAK 2 (Pak2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PAK2 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP815882MO CSB-EP815882MO CSB-BP815882MO CSB-MP815882MO CSB-EP815882MO-B |
Recombinant Mouse Serine/threonine-protein kinase PAK 2 (Pak2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
