PABPC1
PABPC1 is a protein in humans that is encoded by PABPC1 gene. Binds the poly(A) tail of mRNA, including that of its own transcript, and regulates processes of mRNA metabolism such as pre-mRNA splicing and mRNA stability. Its function in translational initiation regulation can either be enhanced by PAIP1 or repressed by PAIP2. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo. Involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. Involved in regulation of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons; for the recognition of premature termination codons (PTC) and initiation of NMD a competitive interaction between UPF1 and PABPC1 with the ribosome-bound release factors is proposed. By binding to long poly(A) tails, may protect them from uridylation by ZCCHC6/ZCCHC11 and hence contribute to mRNA stability.
PABPC1 Antibodies
PABPC1 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA017352GA01HU | PABPC1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
| CSB-PA829516 | PABPC1 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA175056 | PABPC1 Antibody | Human,Mouse,Rat | ELISA,WB |
PABPC1 Proteins
PABPC1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP017352HU CSB-BP017352HU CSB-MP017352HU CSB-EP017352HU-B |
Recombinant Human Polyadenylate-binding protein 1 (PABPC1), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP017352HU | Recombinant Human Polyadenylate-binding protein 1 (PABPC1), partial | E.coli |
PABPC1 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP017352MO CSB-EP017352MO CSB-BP017352MO CSB-MP017352MO CSB-EP017352MO-B |
Recombinant Mouse Polyadenylate-binding protein 1 (Pabpc1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PABPC1 Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP017352BO CSB-EP017352BO CSB-BP017352BO CSB-MP017352BO CSB-EP017352BO-B |
Recombinant Bovine Polyadenylate-binding protein 1 (PABPC1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PABPC1 Proteins for Pongo abelii (Sumatran orangutan)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP725331PYX CSB-EP725331PYX CSB-BP725331PYX CSB-MP725331PYX CSB-EP725331PYX-B |
Recombinant Pongo abelii Polyadenylate-binding protein 1 (PABPC1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PABPC1 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP861666RA CSB-EP861666RA CSB-BP861666RA CSB-MP861666RA CSB-EP861666RA-B |
Recombinant Rat Polyadenylate-binding protein 1 (Pabpc1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
