NTN1
NTN1，即軸突生長誘向因子1，是一種蛋白質(zhì)，由α-螺旋結(jié)構(gòu)組成，并由NTN1基因編碼。這種蛋白質(zhì)在神經(jīng)元的發(fā)育過程中扮演著重要的角色。NTN1通過與其受體識(shí)別并結(jié)合，引導(dǎo)神經(jīng)元軸突的生長和突觸的形成。這種結(jié)合通常依賴于Ca2+離子的存在，通過受體激活內(nèi)源性信號(hào)傳導(dǎo)通路，最終影響神經(jīng)元的發(fā)育和功能。此外，Netrin-1能夠抑制腫瘤細(xì)胞的凋亡（細(xì)胞死亡），并促進(jìn)新血管生成以及控制成纖維細(xì)胞。Netrin-1還涉及上皮間質(zhì)轉(zhuǎn)化（EMT）過程。EMT與腫瘤的發(fā)生、進(jìn)展、轉(zhuǎn)移以及耐藥性緊密相關(guān)。阻斷Netrin-1可以抑制上皮細(xì)胞間質(zhì)轉(zhuǎn)化過程，進(jìn)而對(duì)腫瘤的發(fā)展產(chǎn)生重要影響。
熱銷產(chǎn)品
Recombinant Human Netrin-1 (NTN1)
驗(yàn)證數(shù)據(jù)
CSB-YP016127HU
來源：Yeast
CSB-EP016127HU
來源：E.coli
CSB-BP016127HU
來源：Baculovirus
CSB-MP016127HU
來源：Mammalian cell
CSB-EP016127HU-B
來源：In Vivo Biotinylation in E.coli
NTN1 Antibodies
NTN1 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA003404 | NTN1 Antibody | Human,Mouse,Rat,Monkey | WB, IHC, ELISA |
| CSB-PA006035 | NTN1 Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA016127LA01HU | NTN1 Antibody | Human | ELISA, WB, IHC |
| CSB-PA016127LC01HU | NTN1 Antibody, FITC conjugated | Human | |
| CSB-PA016127LD01HU | NTN1 Antibody, Biotin conjugated | Human | ELISA |
NTN1 Proteins
NTN1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP016127HU CSB-EP016127HU CSB-BP016127HU CSB-MP016127HU CSB-EP016127HU-B |
Recombinant Human Netrin-1 (NTN1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NTN1 ELISA Kit
NTN1 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E11899h | Human Netrin-1,Ntn1 ELISA Kit | serum, plasma, cell culture supernates | 7.81 pg/mL |
