NOD2
Nucleotide-binding oligomerization domain-containing protein 2 is a protein in humans that is encoded by NOD2 gene. Involved in gastrointestinal immunity. Upon stimulation by muramyl dipeptide (MDP), a fragment of bacterial peptidoglycan, binds the proximal adapter receptor-interacting RIPK2, which recruits ubiquitin ligases as XIAP, BIRC2, BIRC3, INAVA and the LUBAC complex, triggering activation of MAP kinases and activation of NF-kappa-B signaling. This in turn leads to the transcriptional activation of hundreds of genes involved in immune response. Required for MDP-induced NLRP1-dependent CASP1 activation and IL1B release in macrophages.
NOD2 Antibodies
NOD2 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA015915GA01HU | NOD2 Antibody | Human | ELISA,WB |
| CSB-PA446192 | NOD2 Antibody | Human | ELISA,IHC |
| CSB-PA876985 | NOD2 Antibody | Human | ELISA,IHC |
| CSB-PA881021LA01HU | NOD2 Antibody | Human | ELISA, IHC, IF |
| CSB-PA881021LB01HU | NOD2 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA881021LC01HU | NOD2 Antibody, FITC conjugated | Human | |
| CSB-PA881021LD01HU | NOD2 Antibody, Biotin conjugated | Human | ELISA |
NOD2 Proteins
NOD2 Proteins for Hylobates lar (Common gibbon)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP681503HXW CSB-EP681503HXW CSB-BP681503HXW CSB-MP681503HXW CSB-EP681503HXW-B |
Recombinant Hylobates lar Nucleotide-binding oligomerization domain-containing protein 2 (NOD2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NOD2 Proteins for Pan troglodytes (Chimpanzee)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP687490EQV CSB-EP687490EQV CSB-BP687490EQV CSB-MP687490EQV CSB-EP687490EQV-B |
Recombinant Pan troglodytes Nucleotide-binding oligomerization domain-containing protein 2 (NOD2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NOD2 Proteins for Bos taurus (Bovine)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP732277BO CSB-BP732277BO CSB-MP732277BO CSB-EP732277BO-B |
Recombinant Bovine Nucleotide-binding oligomerization domain-containing protein 2 (NOD2), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NOD2 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP818352MO CSB-EP818352MO CSB-BP818352MO CSB-MP818352MO CSB-EP818352MO-B |
Recombinant Mouse Nucleotide-binding oligomerization domain-containing protein 2 (Nod2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NOD2 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP881021HU CSB-EP881021HU CSB-BP881021HU CSB-MP881021HU CSB-EP881021HU-B |
Recombinant Human Nucleotide-binding oligomerization domain-containing protein 2 (NOD2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NOD2 Proteins for BO-Bos taurus (Bovine)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-EP732277BO | Recombinant Bovine Nucleotide-binding oligomerization domain-containing protein 2 (NOD2), partial | E.coli |
NOD2 ELISA Kit
NOD2 ELISA Kit for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL015915HU | Human Nucleotide-binding oligomerization domain-containing protein 2(NOD2) ELISA kit | serum, plasma, ascitic fluid, tissue homogenates, cell lysates | 6.25 pg/mL |
