NINJ1

NINJ1，全稱為Nerve Injury-Induced Protein 1，是一種在神經(jīng)損傷后誘導(dǎo)表達(dá)的細(xì)胞表面蛋白，最初在神經(jīng)系統(tǒng)中發(fā)現(xiàn)。它是一種細(xì)胞間粘附分子，參與多種生物學(xué)過程，尤其是在細(xì)胞損傷和修復(fù)、炎癥反應(yīng)以及細(xì)胞死亡中起著重要作用。NINJ1在多種疾病中發(fā)揮重要作用。作為神經(jīng)損傷誘導(dǎo)蛋白，NINJ1在神經(jīng)再生和修復(fù)中起到關(guān)鍵作用，通過上調(diào)表達(dá)促進(jìn)軸突生長(zhǎng)和神經(jīng)功能恢復(fù)。在炎癥性疾病中，NINJ1的調(diào)控作用使其成為潛在的治療靶點(diǎn)，通過抑制NINJ1可以減少免疫細(xì)胞的過度募集和激活，從而減輕炎癥反應(yīng)。在某些腫瘤中，NINJ1的表達(dá)可能影響腫瘤細(xì)胞的粘附和遷移，進(jìn)而影響腫瘤的侵襲和轉(zhuǎn)移能力。近年來，研究發(fā)現(xiàn)NINJ1抗體可以阻斷其寡聚化，從而預(yù)防細(xì)胞膜破裂，為減少組織損傷提供了新思路，特別是在肝細(xì)胞死亡引發(fā)的疾病中。這一發(fā)現(xiàn)為開發(fā)新的抗炎治療方法提供了重要的理論基礎(chǔ)和潛在的臨床應(yīng)用價(jià)值。

熱銷產(chǎn)品

Recombinant Human Ninjurin-1 (NINJ1) (CSB-CF856441HU)

驗(yàn)證數(shù)據(jù)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

NINJ1 Antibody (CSB-PA856441LA01HU)

驗(yàn)證數(shù)據(jù)

Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA856441LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA856441LA01HU at dilution of 1:100

Immunofluorescent analysis of HepG2 cells using CSB-PA856441LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

Immunofluorescent analysis of A549 cells using CSB-PA856441LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

Human Ninjurin-1(NINJ1) ELISA kit (CSB-EL015808HU)

驗(yàn)證數(shù)據(jù)

貨號(hào)：CSB-EL015808HU

規(guī)格：96T/48T

靈敏度：6.25 pg/mL

檢測(cè)范圍：25 pg/mL-1600 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

NINJ1 Antibody

NINJ1 Protein

NINJ1 ELISA Kit

NINJ1 Antibodies

NINJ1 for Homo sapiens (Human)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA856441LA01HU	NINJ1 Antibody	Human	ELISA, IHC, IF
CSB-PA856441LB01HU	NINJ1 Antibody, HRP conjugated	Human	ELISA
CSB-PA856441LC01HU	NINJ1 Antibody, FITC conjugated	Human
CSB-PA856441LD01HU	NINJ1 Antibody, Biotin conjugated	Human	ELISA

NINJ1 Proteins

NINJ1 Proteins for Homo sapiens (Human)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP856441HU1 CSB-EP856441HU1 CSB-BP856441HU1 CSB-MP856441HU1 CSB-EP856441HU1-B	Recombinant Human Ninjurin-1 (NINJ1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF856441HU	Recombinant Human Ninjurin-1 (NINJ1)	in vitro E.coli expression system
CSB-MP856441HU	Recombinant Human Ninjurin-1 (NINJ1)-VLPs	Mammalian cell