NFATC1
NFATC1，即核因子活化T細(xì)胞1，別名NFAT2、NFATc、NF-ATC、NF-ATc1.2等。它是一種由NFATC1基因編碼的轉(zhuǎn)錄因子，主要在免疫細(xì)胞如T細(xì)胞和B細(xì)胞中表達(dá)，對(duì)免疫應(yīng)答中的基因轉(zhuǎn)錄調(diào)控起關(guān)鍵作用。NFATC1的作用機(jī)制涉及鈣調(diào)磷酸酶的激活，導(dǎo)致其從細(xì)胞質(zhì)轉(zhuǎn)移到細(xì)胞核，進(jìn)而調(diào)控靶基因的表達(dá)。NFATC1參與調(diào)節(jié)免疫反應(yīng)、細(xì)胞增殖、分化和遷移等過程，對(duì)維持免疫系統(tǒng)平衡至關(guān)重要。異常的NFATC1表達(dá)與多種疾病相關(guān)，包括自身免疫疾病、心血管疾病和腫瘤等。
熱銷產(chǎn)品
NFATC1 Antibody (CSB-PA17827A0Rb)
驗(yàn)證數(shù)據(jù)
IHC image of CSB-PA17827A0Rb diluted at 1:1200 and staining in paraffin-embedded human appendix tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Immunofluorescent analysis of HepG2 cells using CSB-PA17827A0Rb at dilution of 1: 100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
NFATC1 Antibodies
NFATC1 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA005617 | NFATC1 Antibody | Human,Mouse | WB, ELISA |
| CSB-PA020078 | Phospho-NFATC1 (S294) Antibody | Human,Mouse | IHC, ELISA |
| CSB-PA239200 | NFATC1 Antibody | Human,Mouse | ELISA,IHC |
| CSB-PA17827A0Rb | NFATC1 Antibody | Human | ELISA, IHC, IF |
| CSB-PA17827C0Rb | NFATC1 Antibody, FITC conjugated | Human | |
| CSB-PA17827D0Rb | NFATC1 Antibody, Biotin conjugated | Human | ELISA |
NFATC1 Proteins
NFATC1 Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP015745BO CSB-EP015745BO CSB-BP015745BO CSB-MP015745BO CSB-EP015745BO-B |
Recombinant Bovine Nuclear factor of activated T-cells, cytoplasmic 1 (NFATC1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NFATC1 Proteins for Sus scrofa (Pig)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP015745PI CSB-EP015745PI CSB-BP015745PI CSB-MP015745PI CSB-EP015745PI-B |
Recombinant Pig Nuclear factor of activated T-cells, cytoplasmic 1 (NFATC1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NFATC1 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP015745MO CSB-EP015745MO CSB-BP015745MO CSB-MP015745MO CSB-EP015745MO-B |
Recombinant Mouse Nuclear factor of activated T-cells, cytoplasmic 1 (Nfatc1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NFATC1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP015745HU CSB-EP015745HU CSB-BP015745HU CSB-MP015745HU CSB-EP015745HU-B |
Recombinant Human Nuclear factor of activated T-cells, cytoplasmic 1 (NFATC1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
