NBN
Nibrin is a protein in humans that is encoded by NBN gene. Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11. RAD50 may be required to bind DNA ends and hold them in close proximity. NBN modulate the DNA damage signal sensing by recruiting PI3/PI4-kinase family members ATM, ATR, and probably DNA-PKcs to the DNA damage sites and activating their functions.
NBN Antibodies
NBN for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA015486GA01HU | NBN Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA069758 | Phospho-NBN (Ser343) Antibody | Human | ELISA,WB |
| CSB-PA985787 | NBN (Ab-343) Antibody | Human | ELISA,WB,IHC |
| CSB-PA252258 | NBN Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA003451 | NBN Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA020027 | Phospho-NBN (S343) Antibody | Human,Rat | WB, ELISA |
| CSB-PA020028 | Phospho-NBN (S278) Antibody | Human | WB, IF, ELISA |
| CSB-PA020029 | NBN Antibody | Human | WB, IHC, IF, ELISA |
| CSB-PA020030 | NBN Antibody | Human,Rat | WB, IHC, ELISA |
| CSB-PA170330 | NBN Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA229808 | NBN Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-RA015486A343phHU | Phospho-NBN (S343) Recombinant Monoclonal Antibody | Human | ELISA, WB |
NBN Proteins
NBN Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP015486HU CSB-EP015486HU CSB-BP015486HU CSB-MP015486HU CSB-EP015486HU-B |
Recombinant Human Nibrin (NBN) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NBN Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP015486DIL CSB-EP015486DIL CSB-BP015486DIL CSB-MP015486DIL CSB-EP015486DIL-B |
Recombinant Danio rerio Nibrin (nbn), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NBN Proteins for Pongo abelii (Sumatran orangutan)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP015486PYX CSB-EP015486PYX CSB-BP015486PYX CSB-MP015486PYX CSB-EP015486PYX-B |
Recombinant Pongo abelii Nibrin (NBN), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NBN Proteins for Gallus gallus (Chicken)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP015486CH CSB-EP015486CH CSB-BP015486CH CSB-MP015486CH CSB-EP015486CH-B |
Recombinant Chicken Nibrin (NBN), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NBN Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP015486RA CSB-EP015486RA CSB-BP015486RA CSB-MP015486RA CSB-EP015486RA-B |
Recombinant Rat Nibrin (Nbn) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NBN Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP015486MO CSB-EP015486MO CSB-BP015486MO CSB-MP015486MO CSB-EP015486MO-B |
Recombinant Mouse Nibrin (Nbn) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
