MYL7
Atrial Light Chain-2 (ALC-2) also known as Myosin regulatory light chain 2, atrial isoform (MLC2a) is a protein that in humans is encoded by the MYL7 gene. ALC-2 expression is restricted to cardiac muscle atria in healthy individuals, where it functions to modulate cardiac development and contractility. In human diseases, including hypertrophic cardiomyopathy, dilated cardiomyopathy, ischemic cardiomyopathy and others, ALC-2 expression is altered. Human ALC-2 is phosphorylated at its N-terminus at Serine-15 by a cardiac-specific myosin light chain kinase; interestingly, ALC-2 has a Serine at position 14, which is an Asparagine in the ventricular isoform that is shown to be deamidated (thus producing a negative charge similar to phosphorylation). Whether Serine-14 of human ALC-2 is also phosphorylated remains to be determined. Endogenous phosphorylation level is around 30% of the total ALC-2.
MYL7 Antibodies
MYL7 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA015316GA01HU | MYL7 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA040132 | MYL7 Antibody | Human,Mouse,Rat,Monkey | WB, ELISA |
| CSB-PA889545ESR1HU | MYL7 Antibody | Human, Mouse | ELISA, WB, IHC |
MYL7 Proteins
MYL7 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP889545MO CSB-EP889545MO CSB-BP889545MO CSB-MP889545MO CSB-EP889545MO-B |
Recombinant Mouse Myosin regulatory light chain 2, atrial isoform (Myl7) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MYL7 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-EP889545HU | Recombinant Human Myosin regulatory light chain 2, atrial isoform (MYL7) | E.coli |
