MOG
MOG，即髓鞘少突膠質(zhì)細(xì)胞糖蛋白,別名BTN6、BTNL11、MGC26137、MOG AluA、MOG AluB等。是一種主要在中樞神經(jīng)系統(tǒng)少突膠質(zhì)細(xì)胞膜表面及髓鞘最外層表達(dá)的蛋白質(zhì)，屬于免疫球蛋白超家族成員之一。MOG抗體相關(guān)疾病（MOG-IgG associated disorders, MOGAD）是近年來新認(rèn)識的免疫介導(dǎo)的中樞神經(jīng)系統(tǒng)炎性脫髓鞘疾病，與多發(fā)性硬化（MS）和視神經(jīng)脊髓炎譜系疾病（NMOSD）不同，它是一種獨(dú)立的疾病實(shí)體。MOGAD的發(fā)病機(jī)制可能涉及MOG特異性T濾泡輔助細(xì)胞促進(jìn)B細(xì)胞分化，產(chǎn)生大量MOG-IgG，這些抗體進(jìn)入中樞神經(jīng)系統(tǒng)后與MOG結(jié)合，通過補(bǔ)體和抗體途徑介導(dǎo)細(xì)胞殺傷作用，導(dǎo)致少突膠質(zhì)細(xì)胞損傷和脫髓鞘。MOGAD的臨床表現(xiàn)多樣，包括視神經(jīng)炎、腦膜腦炎、腦干腦炎、脊髓炎等，兒童中較成人更常見，且預(yù)后相對較好。
熱銷產(chǎn)品
Recombinant Human Myelin-oligodendrocyte glycoprotein (MOG), partial (CSB-MP619083HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
MOG Antibody (CSB-PA619083ESR2HU)
驗(yàn)證數(shù)據(jù)
Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA619083ESR2HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA619083ESR2HU at dilution of 1:100
Human Myelin-oligodendrocyte glycoprotein(MOG) ELISA kit (CSB-EL014709HU)
驗(yàn)證數(shù)據(jù)
貨號：CSB-EL014709HU
規(guī)格：96T/48T
靈敏度：3.9 pg/mL
檢測范圍：15.6 pg/mL-1000 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
MOG Antibodies
MOG for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA014709GA01HU | MOG Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA619083ESR2HU | MOG Antibody | Human | ELISA, IHC |
MOG Proteins
MOG Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP619083HU CSB-BP619083HU CSB-EP619083HU-B |
Recombinant Human Myelin-oligodendrocyte glycoprotein (MOG), partial | Yeast Baculovirus In Vivo Biotinylation in E.coli |
| CSB-EP619083HU | Recombinant Human Myelin-oligodendrocyte glycoprotein (MOG), partial | E.coli |
| CSB-MP619083HU(A4) | Recombinant Human Myelin-oligodendrocyte glycoprotein (MOG)-VLPs, Fluorescent | Mammalian cell |
| CSB-MP619083HU | Recombinant Human Myelin-oligodendrocyte glycoprotein (MOG), partial | Mammalian cell |
MOG ELISA Kit
MOG ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL014709HU | Human Myelin-oligodendrocyte glycoprotein(MOG) ELISA kit | serum, plasma, tissue homogenates | 3.9 pg/mL |
