MME

MME，全名為膜金屬內(nèi)肽酶（membrane metalloendopeptidase），也被稱為中性內(nèi)肽酶、腦啡肽酶、神經(jīng)肽酶等。MME蛋白在細(xì)胞表面表達(dá)，主要功能是降解多肽，包括阿片肽、緩激肽、P物質(zhì)和神經(jīng)降壓素肽等。它在神經(jīng)遞質(zhì)和激素的降解中起關(guān)鍵作用，與多種生理過程相關(guān)。MME蛋白與阿爾茨海默病、多發(fā)性硬化癥、癌癥等多種疾病有關(guān)，因此成為藥物研發(fā)的熱點(diǎn)靶點(diǎn)。目前，針對(duì)MME蛋白的藥物研發(fā)主要集中在開發(fā)能夠抑制其活性的藥物，以治療相關(guān)疾病。

熱銷產(chǎn)品

Recombinant Human Neprilysin (MME), partial (CSB-YP014653HU)

驗(yàn)證數(shù)據(jù)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Based on the SEQUEST from database of Yeast host and target protein, the LC-MS/MS Analysis result of CSB-YP014653HU could indicate that this peptide derived from Yeast-expressed Homo sapiens (Human) MME.

MME Recombinant Monoclonal Antibody (CSB-RA940661A0HU)

驗(yàn)證數(shù)據(jù)

Western Blot
Positive WB detected in: U251 whole cell lysate
All lanes: MME antibody at 1:1500
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 86 kDa
Observed band size: 100 kDa

MME Antibody

MME Protein

MME ELISA Kit

MME Antibodies

MME for Homo sapiens (Human)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA014653GA01HU	MME Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA985136	MME Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA005556	MME Antibody	Human,Mouse,Rat	WB, ELISA
CSB-PA086078	MME Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA927708	MME Antibody	Human,Mouse,Rat	ELISA,IHC
CSB-PA897259	MME Antibody	Human,Mouse,Rat	IHC,ELISA
CSB-PA014653LA01HU	MME Antibody	Human	ELISA, IHC
CSB-PA014653LB01HU	MME Antibody, HRP conjugated	Human	ELISA
CSB-PA014653LC01HU	MME Antibody, FITC conjugated	Human
CSB-PA014653LD01HU	MME Antibody, Biotin conjugated	Human	ELISA
CSB-PA014653LA11HU	MME Antibody	Human	ELISA, IHC, IF
CSB-PA014653LB11HU	MME Antibody, HRP conjugated	Human	ELISA
CSB-PA014653LC11HU	MME Antibody, FITC conjugated	Human
CSB-PA014653LD11HU	MME Antibody, Biotin conjugated	Human	ELISA
CSB-RA940661A0HU	MME Recombinant Monoclonal Antibody	Human	ELISA, WB
CSB-RA187479A0HU	MME Recombinant Monoclonal Antibody	Human	ELISA, IHC

MME for H, M, R

產(chǎn)品貨號(hào)	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-MA000230	MME Monoclonal Antibody	Human,Mouse,Rat	ELISA,IHC

MME Proteins

MME Proteins for Sus scrofa (Pig)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP014653PI CSB-EP014653PI CSB-BP014653PI CSB-MP014653PI CSB-EP014653PI-B	Recombinant Pig Neprilysin (MME)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

MME Proteins for Homo sapiens (Human)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP014653HU	Recombinant Human Neprilysin (MME), partial	Yeast
CSB-EP014653HU CSB-BP014653HU CSB-MP014653HU CSB-EP014653HU-B	Recombinant Human Neprilysin (MME), partial	E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

MME Proteins for Oryctolagus cuniculus (Rabbit)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP014653RB1 CSB-EP014653RB1 CSB-BP014653RB1 CSB-MP014653RB1 CSB-EP014653RB1-B	Recombinant Rabbit Neprilysin (MME), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF014653RB	Recombinant Rabbit Neprilysin (MME)	in vitro E.coli expression system

MME Proteins for Rattus norvegicus (Rat)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP362251RA CSB-EP362251RA CSB-BP362251RA CSB-MP362251RA CSB-EP362251RA-B	Recombinant Rat Neprilysin (Mme), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

MME Proteins for Pongo abelii (Sumatran orangutan)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP722446PYX CSB-EP722446PYX CSB-BP722446PYX CSB-MP722446PYX CSB-EP722446PYX-B	Recombinant Pongo abelii Neprilysin (MME), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

MME Proteins for Mus musculus (Mouse)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP723409MO CSB-EP723409MO CSB-BP723409MO CSB-MP723409MO CSB-EP723409MO-B	Recombinant Mouse Neprilysin (Mme), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli