MIB1
MIB1 is a protein in humans that is encoded by MIB1 gene. E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. Probably mediates ubiquitination and subsequent proteasomal degradation of DAPK1, thereby antagonizing anti-apoptotic effects of DAPK1 to promote TNF-induced apoptosis (By similarity). Involved in ubiquitination of centriolar satellite CEP131, CEP290 and PCM1 proteins and hence inhibits primary cilium formation in proliferating cells. Mediates 'Lys-63'-linked polyubiquitination of TBK1, which probably participates in kinase activation.
MIB1 Antibodies
MIB1 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA13289A0Rb | MIB1 Antibody | Human | ELISA, WB, IHC, IF |
| CSB-PA13289B0Rb | MIB1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA13289C0Rb | MIB1 Antibody, FITC conjugated | Human | |
| CSB-PA287419 | MIB1 Antibody | Human,Mouse,Rat | WB,ELISA |
MIB1 Proteins
MIB1 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-EP771476HU | Recombinant Human E3 ubiquitin-protein ligase MIB1 (MIB1), partial | E.coli |
| CSB-YP771476HU CSB-EP771476HU CSB-BP771476HU CSB-MP771476HU CSB-EP771476HU-B |
Recombinant Human E3 ubiquitin-protein ligase MIB1 (MIB1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MIB1 Proteins for Xenopus laevis (African clawed frog)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP756962XBE CSB-EP756962XBE CSB-BP756962XBE CSB-MP756962XBE CSB-EP756962XBE-B |
Recombinant Xenopus laevis E3 ubiquitin-protein ligase mib1 (mib1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MIB1 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP768867MO CSB-EP768867MO CSB-BP768867MO CSB-MP768867MO CSB-EP768867MO-B |
Recombinant Mouse E3 ubiquitin-protein ligase MIB1 (Mib1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MIB1 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP773868DIL CSB-EP773868DIL CSB-BP773868DIL CSB-MP773868DIL CSB-EP773868DIL-B |
Recombinant Danio rerio E3 ubiquitin-protein ligase mib1 (mib1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MIB1 Proteins for Drosophila melanogaster (Fruit fly)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP896152DLU CSB-EP896152DLU CSB-BP896152DLU CSB-MP896152DLU CSB-EP896152DLU-B |
Recombinant Drosophila melanogaster E3 ubiquitin-protein ligase mind-bomb (mib1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
