MGAT4A
MGAT4A，即α-1,3-巖藻糖基-糖蛋白4-β-N-乙酰葡糖胺轉(zhuǎn)移酶A，別名GNT-IV、GnT-4a、GNT-IVA。MGAT4A是一種糖基轉(zhuǎn)移酶，主要參與N-糖基化過程，特別是在蛋白質(zhì)的糖鏈合成中。MGAT4A催化N-乙酰葡糖胺（GlcNAc）從UDP-GlcNAc轉(zhuǎn)移到巖藻糖基化糖蛋白的特定糖鏈結(jié)構(gòu)上，這一步驟對(duì)于糖蛋白的正確折疊、穩(wěn)定性和功能至關(guān)重要。MGAT4A通過其酶活性，影響多種細(xì)胞表面受體和信號(hào)分子的功能，包括細(xì)胞黏附分子和免疫調(diào)節(jié)分子。MGAT4A在調(diào)控細(xì)胞信號(hào)傳導(dǎo)、免疫反應(yīng)和腫瘤生物學(xué)中扮演重要角色。MGAT4A的異常表達(dá)或功能失調(diào)與多種疾病相關(guān)，包括某些癌癥類型，可能影響腫瘤細(xì)胞的增殖和轉(zhuǎn)移能力。
熱銷產(chǎn)品
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
MGAT4A Proteins
MGAT4A Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP890937HU CSB-BP890937HU CSB-EP890937HU-B |
Recombinant Human Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A (MGAT4A), partial | Yeast Baculovirus In Vivo Biotinylation in E.coli |
| CSB-EP890937HU | Recombinant Human Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A (MGAT4A), partial | E.coli |
| CSB-MP890937HU | Recombinant Human Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A (MGAT4A), partial | Mammalian cell |
