MAVS
Mitochondrial antiviral-signaling protein is a protein in humans that is encoded by MAVS gene. Required for innate immune defense against viruses. Acts downstream of DDX58/RIG-I and IFIH1/MDA5, which detect intracellular dsRNA produced during viral replication, to coordinate pathways leading to the activation of NF-kappa-B, IRF3 and IRF7, and to the subsequent induction of antiviral cytokines such as IFN-beta and RANTES (CCL5). Peroxisomal and mitochondrial MAVS act sequentially to create an antiviral cellular state. Upon viral infection, peroxisomal MAVS induces the rapid interferon-independent expression of defense factors that provide short-term protection, whereas mitochondrial MAVS activates an interferon-dependent signaling pathway with delayed kinetics, which amplifies and stabilizes the antiviral response.
MAVS Antibodies
MAVS for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA013526GA01HU | MAVS Antibody | Human | ELISA,WB,IF |
| CSB-PA772018ESR2HU | MAVS Antibody | Human | ELISA |
| CSB-PA179571 | MAVS Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA846893 | MAVS Antibody | Human,Mouse | ELISA,WB,IHC |
MAVS Proteins
MAVS Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP721076RA CSB-EP721076RA CSB-BP721076RA CSB-MP721076RA CSB-EP721076RA-B |
Recombinant Rat Mitochondrial antiviral-signaling protein (Mavs), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MAVS Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP772018HU CSB-EP772018HU CSB-BP772018HU CSB-MP772018HU |
Recombinant Human Mitochondrial antiviral-signaling protein (MAVS), partial | Yeast E.coli Baculovirus Mammalian cell |
| CSB-EP772018HUa2 | Recombinant Human Mitochondrial antiviral-signaling protein (MAVS), partial | E.coli |
| CSB-EP772018HUc0 | Recombinant Human Mitochondrial antiviral-signaling protein (MAVS), partial | E.coli |
| CSB-EP772018HU-B | Recombinant Human Mitochondrial antiviral-signaling protein (MAVS), partial,Biotinylated | E.coli |
MAVS Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP844990MO CSB-EP844990MO CSB-BP844990MO CSB-MP844990MO CSB-EP844990MO-B |
Recombinant Mouse Mitochondrial antiviral-signaling protein (Mavs), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
