LRP6
Low-density lipoprotein receptor-related protein 6 is a protein in humans that is encoded by LRP6 gene. Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in bone formation. The Wnt-induced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3B-complex to the cell surface promoting the formation of signalsomes and inhibiting AXIN1/GSK3-mediated phosphorylation and destruction of beta-catenin.
LRP6 Antibodies
LRP6 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA013102ESR2HU | LRP6 Antibody | Human | ELISA, IHC |
| CSB-PA234397 | LRP6 Antibody | Human,Mouse | ELISA,IHC |
LRP6 Proteins
LRP6 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP013102HU CSB-EP013102HU CSB-BP013102HU CSB-MP013102HU CSB-EP013102HU-B |
Recombinant Human Low-density lipoprotein receptor-related protein 6 (LRP6), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
LRP6 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP013102MO CSB-EP013102MO CSB-BP013102MO CSB-MP013102MO CSB-EP013102MO-B |
Recombinant Mouse Low-density lipoprotein receptor-related protein 6 (Lrp6), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
LRP6 ELISA Kit
LRP6 ELISA Kit for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E08952h | Human low-density lipoprotein-receptor-related protein,LRP-6 ELISA Kit | serum, tissue homogenates, cell lysates | 0.078 ng/mL |
