LIF
白血病抑制因子（LIF）屬于IL-6超家族的細胞因子。LIF可在不同的細胞中表達，包括活化的T細胞、單核細胞、膠質細胞、肝臟成纖維細胞、骨髓基質細胞、胚胎干細胞、胸腺上皮細胞和許多其他細胞。LIF的作用是通過一個高親和力的受體復合物介導的，該復合物由一個低親和力的LIFRβ（也稱為LIFR）和一個高親和力的亞單位gp130組成，從而激活STAT、p21ras/MAP和PI-3信號途徑。LIF作為具有多種生物功能的細胞因子，可參與骨髓性白血病細胞的造血分化，腎臟發育過程中間質向上皮的轉化。在癌癥中也有強大的功能，參與了腫瘤生長和進展的一些關鍵過程，包括免疫耐受、PNI、化療和放射抗性、癌癥干細胞樣表型維持、EMT和TME發展。
Recombinant Human LIF 活性蛋白實驗驗證數據
CSB-MP006254HU(F1) is detected by Mouse anti-6*His monoclonal antibody.
Measured by its binding ability in a functional ELISA. Immobilized human LIF at 2 μg/ml can bind human LIFR (CSB-MP012929HUi9), the EC50 is 22.58-30.24 ng/ml.
LIF Antibodies
LIF for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA012928ESR2HU | LIF Antibody | Human | ELISA |
| CSB-PA004761 | LIF Antibody | Human | WB, ELISA |
| CSB-PA198481 | LIF Antibody | Human,Mouse,Rat | ELISA,IHC |
LIF Proteins
LIF Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-EP012928HU CSB-BP012928HU CSB-EP012928HU-B |
Recombinant Human Leukemia inhibitory factor (LIF) | E.coli Baculovirus In Vivo Biotinylation in E.coli |
| CSB-AP002221HU | Recombinant Human Leukemia inhibitory factor protein (LIF) | E.Coli |
| CSB-AP004001HU | Recombinant Human Leukemia inhibitory factor (LIF) (Active) | E.coli |
| CSB-MP012928HUd9 | Recombinant Human Leukemia inhibitory factor (LIF) (Active) | Mammalian cell |
| CSB-MP012928HU | Recombinant Human Leukemia inhibitory factor (LIF) (Active) | Mammalian cell |
| CSB-YP012928HU | Recombinant Human Leukemia inhibitory factor (LIF) | Yeast |
| CSB-MP012928HU-WD | Recombinant Human Leukemia inhibitory factor (LIF) (Active) | Mammalian cell |
LIF Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-EP012928RA CSB-BP012928RA CSB-EP012928RA-B |
Recombinant Rat Leukemia inhibitory factor (Lif) | E.coli Baculovirus In Vivo Biotinylation in E.coli |
LIF Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-BP012928MO CSB-EP012928MO-B |
Recombinant Mouse Leukemia inhibitory factor (Lif) | Baculovirus In Vivo Biotinylation in E.coli |
LIF Proteins for Mustela vison (American mink) (Neovison vison)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP528926MVE CSB-EP528926MVE CSB-BP528926MVE CSB-MP528926MVE CSB-EP528926MVE-B |
Recombinant Mustela vison Leukemia inhibitory factor (LIF) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
LIF Proteins for Bos taurus (Bovine)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP637735BO CSB-EP637735BO CSB-BP637735BO CSB-MP637735BO CSB-EP637735BO-B |
Recombinant Bovine Leukemia inhibitory factor (LIF) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
LIF ELISA Kit
LIF ELISA Kit for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E04651h | Human Leukemia inhibitory factor,LIF ELISA kit | serum, plasma, cell culture supernates, tissue homogenates | 2.34 pg/mL |
LIF ELISA Kit for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E04652m | Mouse Leukemia inhibitory factor,LIF ELISA kit | serum, plasma, tissue homogenates | 3.9 pg/mL |
LIF ELISA Kit for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E07432r | Rat leukemia inhibitory factor,LIF ELISA Kit | serum, plasma, bronchoalveolar lavage fluid, tissue homogenates | 0.078 ng/mL |
