LCK
Tyrosine-protein kinase Lck is a protein in humans that is encoded by LCK gene. Non-receptor tyrosine-protein kinase that plays an essential role in the selection and maturation of developing T-cells in the thymus and in the function of mature T-cells. Plays a key role in T-cell antigen receptor (TCR)-linked signal transduction pathways. Constitutively associated with the cytoplasmic portions of the CD4 and CD8 surface receptors. Association of the TCR with a peptide antigen-bound MHC complex facilitates the interaction of CD4 and CD8 with MHC class II and class I molecules, respectively, thereby recruiting the associated LCK protein to the vicinity of the TCR/CD3 complex. LCK then phosphorylates tyrosine residues within the immunoreceptor tyrosine-based activation motifs (ITAM) of the cytoplasmic tails of the TCR-gamma chains and CD3 subunits, initiating the TCR/CD3 signaling pathway.
LCK Antibodies
LCK for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA012806GA01HU | LCK Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA012806LA01HU | LCK Antibody | Human | ELISA, IHC, IF, IP |
| CSB-PA012806LB01HU | LCK Antibody, HRP conjugated | Human | ELISA |
| CSB-PA096222 | Phospho-LCK (Tyr394) Antibody | Human,Mouse | ELISA,WB |
| CSB-PA285947 | Phospho-LCK (Tyr505) Antibody | Human,Mouse | ELISA,WB |
| CSB-PA977883 | LCK (Ab-394) Antibody | Human,Mouse | ELISA,WB |
| CSB-PA003142 | LCK Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA009788 | Phospho-LCK (Y192) Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA009790 | Phospho-LCK (S540) Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA009793 | Phospho-LCK (Y393) Antibody | Human,Mouse,Rat | WB, IF, ELISA |
| CSB-PA009794 | Phospho-LCK (Y505) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA009795 | LCK Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA009798 | LCK Antibody | Human,Mouse,Rat | WB, IF, ELISA |
| CSB-PA009802 | LCK Antibody | Human,Mouse,Rat | WB, IF, ELISA |
LCK Proteins
LCK Proteins for Gallus gallus (Chicken)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP012806CH CSB-EP012806CH CSB-BP012806CH CSB-MP012806CH CSB-EP012806CH-B |
Recombinant Chicken Proto-oncogene tyrosine-protein kinase LCK (LCK), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
LCK Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP012806HU CSB-BP012806HU CSB-MP012806HU CSB-EP012806HU-B |
Recombinant Human Tyrosine-protein kinase Lck (LCK) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP012806HU | Recombinant Human Tyrosine-protein kinase Lck (LCK) | E.coli |
| CSB-EP012806HUa2 | Recombinant Human Tyrosine-protein kinase Lck (LCK) | E.coli |
LCK Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP012806MO CSB-EP012806MO CSB-BP012806MO CSB-MP012806MO CSB-EP012806MO-B |
Recombinant Mouse Proto-oncogene tyrosine-protein kinase LCK (Lck) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
LCK Proteins for Aotus nancymaae (Ma's night monkey)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP712729AUV CSB-EP712729AUV CSB-BP712729AUV CSB-MP712729AUV CSB-EP712729AUV-B |
Recombinant Aotus nancymaae Tyrosine-protein kinase Lck (LCK), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
LCK Proteins for Saimiri sciureus (Common squirrel monkey)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP853302SWD CSB-EP853302SWD CSB-BP853302SWD CSB-MP853302SWD CSB-EP853302SWD-B |
Recombinant Saimiri sciureus Proto-oncogene tyrosine-protein kinase LCK (LCK), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
