ITIH4

ITIH4，全稱為inter-alpha-trypsin inhibitor heavy chain 4，是一種參與炎癥反應(yīng)的II型急性期蛋白，也被稱為PK120、Gp120、ITIHL1、ITI-HC4等。該蛋白在創(chuàng)傷引起的炎癥反應(yīng)中發(fā)揮作用，可能參與肝臟的發(fā)育或再生過程。研究表明，ITIH4蛋白在慢性阻塞性肺疾病（COPD）患者的血清中含量低于健康人，且與空氣污染物的關(guān)聯(lián)性較高。此外，ITIH4蛋白還可能成為預(yù)測COPD病情進(jìn)展的生物標(biāo)志物，為評(píng)估治療效果提供依據(jù)。在藥物研發(fā)方面，ITIH4蛋白已被關(guān)注，有望成為開發(fā)新型治療COPD等疾病藥物的重要靶點(diǎn)。

熱銷產(chǎn)品

Recombinant Human Inter-alpha-trypsin inhibitor heavy chain H4 (ITIH4), partial (CSB-EP617923HU)

驗(yàn)證數(shù)據(jù)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

ITIH4 Antibody (CSB-PA011897LA01HU)

驗(yàn)證數(shù)據(jù)

IHC image of CSB-PA011897LA01HU diluted at 1:300 and staining in paraffin-embedded human liver tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

IHC image of CSB-PA011897LA01HU diluted at 1:300 and staining in paraffin-embedded human liver cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

ITIH4 Antibody

ITIH4 Protein

ITIH4 ELISA Kit

ITIH4 Antibodies

ITIH4 for Homo sapiens (Human)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA011897LA01HU	ITIH4 Antibody	Human	ELISA, IHC
CSB-PA011897LB01HU	ITIH4 Antibody, HRP conjugated	Human	ELISA
CSB-PA011897LD01HU	ITIH4 Antibody, Biotin conjugated	Human	ELISA
CSB-PA011897YA01HU	ITIH4 Antibody	Human	ELISA, IHC
CSB-PA011897YD01HU	ITIH4 Antibody, Biotin conjugated	Human	ELISA
CSB-PA011276	Cleaved-ITIH4 (R661) Antibody	Human	IHC, ELISA

ITIH4 Proteins

ITIH4 Proteins for Homo sapiens (Human)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP617923HU	Recombinant Human Inter-alpha-trypsin inhibitor heavy chain H4 (ITIH4)，partial	Yeast
CSB-EP617923HU	Recombinant Human Inter-alpha-trypsin inhibitor heavy chain H4 (ITIH4), partial	E.coli
CSB-BP617923HU CSB-MP617923HU CSB-EP617923HU-B	Recombinant Human Inter-alpha-trypsin inhibitor heavy chain H4 (ITIH4)，partial	Baculovirus Mammalian cell In Vivo Biotinylation in E.coli