IL2RA
白介素-2受體α亞基（IL2RA）也被稱為Tac抗原、P55、CD25，是一種細(xì)胞表面蛋白，與β亞基（CD122）、γ亞基（CD132）共同組成白介素-2受體。該蛋白主要參與免疫細(xì)胞的信號(hào)傳遞，尤其在維持免疫耐受和調(diào)節(jié)性T細(xì)胞功能中起核心作用。IL2RA在免疫系統(tǒng)中發(fā)揮重要作用，與T細(xì)胞的增殖、存活和分化密切相關(guān)。IL2RA蛋白的表達(dá)和功能異常與類風(fēng)濕性關(guān)節(jié)炎、1型糖尿病等疾病的發(fā)生發(fā)展密切相關(guān)。首個(gè)基于IL-2的藥物（aldesleukin：重組IL-2）于1992年被FDA批準(zhǔn)，用于治療轉(zhuǎn)移性腎癌；1998年，該藥又被批準(zhǔn)用于治療轉(zhuǎn)移性黑色素瘤。目前，IL2RA作為免疫調(diào)節(jié)研究領(lǐng)域的熱點(diǎn)，相關(guān)藥物研發(fā)仍在持續(xù)進(jìn)行中。
熱銷產(chǎn)品
Recombinant Human Interleukin-2 receptor subunit alpha (IL2RA), partial (Active) (CSB-MP011649HU3)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity
Measured by its binding ability in a functional ELISA. Immobilized Human IL2RA at 2μg/mL can bind Anti-IL2RA recombinant antibody (CSB-RA011649MA1HU)，the EC50 is 2.463-3.353 ng/mL.
Activity
Measured by its binding ability in a functional ELISA. Immobilized Human IL2RA at 2μg/mL can bindHuman IL2(CSB-MP011629HU)，the EC50 is 1.693-2.039 ng/mL.
IL2RA (Basiliximab) Recombinant Monoclonal Antibody (CSB-RA011649MA1HU)
驗(yàn)證數(shù)據(jù)
The Binding Activity of Human IL2RA with Anti-IL2RA Recombinant Antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human IL2RA (CSB-MP011649HU3) at 2 μg/mL can bind Anti-IL2RA recombinant antibody , the EC50 is 2.463-3.353 ng/mL.
Immunofluorescence staining of Hela cell with CSB-RA011649MA1HU at 1:30, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-human IgG(H+L).
Immunofluorescence staining of HEPG2 cell with CSB-RA011649MA1HU at 1:30, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-human IgG(H+L).
Human soluble interleukin-2 receptor,IL-2sRα ELISA kit (CSB-E04629h)
驗(yàn)證數(shù)據(jù)
貨號(hào)：CSB-E04629h
規(guī)格：96T/48T
靈敏度：19.5 pg/mL
檢測(cè)范圍：78 pg/mL-5000 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
IL2RA Antibodies
IL2RA for H
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-MA000266 | IL2RA Monoclonal Antibody | Human | ELISA,IHC |
IL2RA for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA005198 | IL2RA Antibody | Human | WB, ELISA |
| CSB-PA009542 | Phospho-IL2RA (S268) Antibody | Human | WB, IHC, IF, ELISA |
| CSB-PA009543 | IL2RA Antibody | Human | WB, IF, ELISA |
| CSB-PA904921 | IL2RA Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA013952 | IL2RA Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA011649LA01HU | IL2RA Antibody | Human, Rat | ELISA, WB, IHC, IF |
| CSB-PA011649LC01HU | IL2RA Antibody, FITC conjugated | Human | |
| CSB-PA011649LD01HU | IL2RA Antibody, Biotin conjugated | Human | ELISA |
| CSB-RA011649MA1HU | IL2RA (Basiliximab) Recombinant Monoclonal Antibody | Human | ELISA, IF |
IL2RA Proteins
IL2RA Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP011649BO1 CSB-EP011649BO1 CSB-BP011649BO1 CSB-MP011649BO1 CSB-EP011649BO1-B |
Recombinant Bovine Interleukin-2 receptor subunit alpha (IL2RA), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF011649BO | Recombinant Bovine Interleukin-2 receptor subunit alpha (IL2RA) | in vitro E.coli expression system |
IL2RA Proteins for Ovis aries (Sheep)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP011649SH1 CSB-EP011649SH1 CSB-BP011649SH1 CSB-MP011649SH1 CSB-EP011649SH1-B |
Recombinant Sheep Interleukin-2 receptor subunit alpha (IL2RA), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF011649SH | Recombinant Sheep Interleukin-2 receptor subunit alpha (IL2RA) | in vitro E.coli expression system |
IL2RA Proteins for Felis catus (Cat) (Felis silvestris catus)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP011649CA1 CSB-EP011649CA1 CSB-BP011649CA1 CSB-MP011649CA1 CSB-EP011649CA1-B |
Recombinant Cat Interleukin-2 receptor subunit alpha (IL2RA), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF011649CA | Recombinant Cat Interleukin-2 receptor subunit alpha (IL2RA) | in vitro E.coli expression system |
IL2RA Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP011649RA1 CSB-EP011649RA1 CSB-BP011649RA1 CSB-MP011649RA1 CSB-EP011649RA1-B |
Recombinant Rat Interleukin-2 receptor subunit alpha (Il2ra), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF011649RA | Recombinant Rat Interleukin-2 receptor subunit alpha (Il2ra) | in vitro E.coli expression system |
IL2RA Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP011649HU1 CSB-EP011649HU1 CSB-BP011649HU1 CSB-MP011649HU1 CSB-EP011649HU1-B |
Recombinant Human Interleukin-2 receptor subunit alpha (IL2RA), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF011649HU | Recombinant Human Interleukin-2 receptor subunit alpha (IL2RA) | in vitro E.coli expression system |
| CSB-EP011649HU2 | Recombinant Human Interleukin-2 receptor subunit alpha (IL2RA), partial | E.coli |
| CSB-MP011649HU3 | Recombinant Human Interleukin-2 receptor subunit alpha (IL2RA), partial (Active) | Mammalian cell |
IL2RA Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP011649MO1 CSB-EP011649MO1 CSB-BP011649MO1 CSB-EP011649MO1-B |
Recombinant Mouse Interleukin-2 receptor subunit alpha (Il2ra), partial | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
| CSB-CF011649MO | Recombinant Mouse Interleukin-2 receptor subunit alpha (Il2ra) | in vitro E.coli expression system |
IL2RA Proteins for Sus scrofa (Pig)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-BP011649PI1 CSB-MP011649PI1 CSB-EP011649PI1-B |
Recombinant Pig Interleukin-2 receptor subunit alpha (IL2RA), partial | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF011649PI | Recombinant Pig Interleukin-2 receptor subunit alpha (IL2RA) | in vitro E.coli expression system |
IL2RA Proteins for Canis familiaris (Dog) (Canis lupus familiaris)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP011649DO1 CSB-EP011649DO1 CSB-BP011649DO1 CSB-MP011649DO1 CSB-EP011649DO1-B |
Recombinant Dog Interleukin-2 receptor subunit alpha (IL2RA), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF011649DO | Recombinant Dog Interleukin-2 receptor subunit alpha (IL2RA) | in vitro E.coli expression system |
IL2RA Proteins for Pan troglodytes (Chimpanzee)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP656443EQV CSB-EP656443EQV CSB-BP656443EQV CSB-MP656443EQV CSB-EP656443EQV-B |
Recombinant Pan troglodytes Interleukin-2 receptor subunit alpha (IL2RA), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IL2RA Proteins for Macaca mulatta (Rhesus macaque)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP689641MOW CSB-EP689641MOW CSB-BP689641MOW CSB-MP689641MOW CSB-EP689641MOW-B |
Recombinant Macaca mulatta Interleukin-2 receptor subunit alpha (IL2RA), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IL2RA ELISA Kit
IL2RA ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E04629h | Human soluble interleukin-2 receptor,IL-2sRα ELISA kit | serum, plasma, tissue homogenates | 19.5 pg/mL |
IL2RA ELISA Kit for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E07440m | Mouse soluble interleukin-2 receptor,sIL-2Rα ELISA kit | serum, plasma, tissue homogenates | 3.9 pg/ml |
