IGFBP7
IGFBP7，全稱為胰島素樣生長(zhǎng)因子結(jié)合蛋白7，也被稱為IGFBP-7、TAF、MAC25、PSF等。該蛋白主要功能是調(diào)節(jié)胰島素樣生長(zhǎng)因子（IGF）在體內(nèi)的可用性，并影響IGF與其受體的結(jié)合。IGFBP7在多種組織中均有表達(dá)，尤其在骨骼肌中表達(dá)較高。研究發(fā)現(xiàn)，IGFBP7在骨骼肌的維持和修復(fù)中發(fā)揮重要作用，與肌肉萎縮等疾病相關(guān)。目前，IGFBP7已成為研究熱點(diǎn)，在藥物研發(fā)方面，針對(duì)其作用機(jī)制的研究有助于開(kāi)發(fā)治療肌肉萎縮、癌癥等疾病的藥物。
熱銷(xiāo)產(chǎn)品
Recombinant Human Insulin-like growth factor-binding protein 7 (IGFBP7) (Active) (CSB-MP620956HUd9)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity
Measured by its binding ability in a functional ELISA. Immobilized Human CD93 (CSB-MP865099HU) at 2 μg/ml can bind Human IGFBP7. The EC50 is 3.405-5.456 ng/mL.
IGFBP7 Antibody (CSB-PA16259A0Rb)
驗(yàn)證數(shù)據(jù)
Western Blot
Positive WB detected in: Rat kidney tissue
All lanes: IGFBP7 antibody at 3.4μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 30, 29 kDa
Observed band size: 30 kDa
IGFBP7 Antibodies
IGFBP7 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類(lèi)型 |
|---|---|---|---|
| CSB-PA009508 | IGFBP7 Antibody | Human,Mouse,Rat | IHC, ELISA |
| CSB-PA082992 | IGFBP7 Antibody | Human,Mouse | ELISA,IHC |
| CSB-PA439452 | IGFBP7 Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA16259A0Rb | IGFBP7 Antibody | Human, Rat | ELISA, WB |
| CSB-PA16259B0Rb | IGFBP7 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA16259C0Rb | IGFBP7 Antibody, FITC conjugated | Human | |
| CSB-PA16259D0Rb | IGFBP7 Antibody, Biotin conjugated | Human | ELISA |
IGFBP7 Proteins
IGFBP7 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-BP620956HU CSB-MP620956HU CSB-EP620956HU-B |
Recombinant Human Insulin-like growth factor-binding protein 7 (IGFBP7) | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-MP620956HUd9 | Recombinant Human Insulin-like growth factor-binding protein 7 (IGFBP7) (Active) | Mammalian cell |
| CSB-EP620956HU | Recombinant Human Insulin-like growth factor-binding protein 7 (IGFBP7) | E.coli |
| CSB-YP620956HU | Recombinant Human Insulin-like growth factor-binding protein 7 (IGFBP7) | Yeast |
IGFBP7 ELISA Kit
IGFBP7 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類(lèi)型 | 靈敏度 |
|---|---|---|---|
| CSB-E17249h | Human Insulin-like growth factor-binding protein 7 (IGFBP7/MAC25/PSF) ELISA kit | serum, plasma, homogenates | 19.5 pg/ml |
