IFNA2
IFNA2（干擾素-α2）是干擾素-α（IFN-α）家族成員之一，具有抗病毒、抗腫瘤和免疫調節功能。它是一種由約165-166個氨基酸殘基組成的蛋白質，分子量約18-21 kDa，具有α-螺旋和β-折疊結構域。IFNA2基因位于人類染色體9上，與其他IFN-α亞型基因聚集。其主要功能包括激活細胞內抗病毒防御機制、抑制腫瘤細胞增殖、促進腫瘤細胞凋亡以及增強免疫細胞活性。IFNA2通過與其受體結合，激活JAK-STAT信號通路，進而磷酸化STAT蛋白，導致它們二聚化并轉移到細胞核中，調控干擾素刺激基因（ISGs）的表達。此外，IFNA2還涉及PI3K-AKT和MAPK信號通路，參與細胞生存、增殖、分化和凋亡等過程。臨床上，IFNA2被用于治療乙型和丙型肝炎以及某些類型的癌癥，盡管治療效果可能受到個體差異、病毒抗性和副作用的影響。
熱銷產品
Recombinant Human Interferon alpha-2 (IFNA2) (CSB-EP360706HUe3)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
IFNA2 Antibodies
IFNA2 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA06504D0Rb | IFNA2 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA06504B0Rb | IFNA2 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA06504A0Rb | IFNA2 Antibody | Human, Mouse, Rat | ELISA,WB?,IHC |
| CSB-PA250552 | IFNA2 Antibody | Human | ELISA,IHC |
| CSB-PA048892 | IFNA2 Antibody | Human | ELISA,IHC |
IFNA2 Proteins
IFNA2 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP360706HU | Recombinant Human Interferon alpha-2 (IFNA2) | Yeast |
| CSB-EP360706HU | Recombinant Human Interferon alpha-2 (IFNA2) | E.coli |
| CSB-AP002761HU | Recombinant Human Interferon alpha-2 protein (IFNA2) | Yeast |
| CSB-AP002771HU | Recombinant Human Interferon alpha-2 protein (IFNA2), partial (Active) | E.Coli |
| CSB-AP002781HU | Recombinant Human Interferon alpha-2 protein (IFNA2) | Yeast |
| CSB-BP360706HU CSB-EP360706HU-B |
Recombinant Human Interferon alpha-2 (IFNA2) | Baculovirus In Vivo Biotinylation in E.coli |
| CSB-AP004191HU | Recombinant Human Interferon alpha-2 (IFNA2) (Active) | E.coli |
| CSB-EP360706HUe3 | Recombinant Human Interferon alpha-2 (IFNA2) | E.coli |
| CSB-MP360706HU | Recombinant Human Interferon alpha-2 (IFNA2) (Active) | Mammalian cell |
| CSB-MP360706HU-WD | Recombinant Human Interferon alpha-2 (IFNA2) (Active) | Mammalian cell |
IFNA2 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-EP365593MO CSB-BP365593MO CSB-EP365593MO-B |
Recombinant Mouse Interferon alpha-2 (Ifna2) | E.coli Baculovirus In Vivo Biotinylation in E.coli |
IFNA2 ELISA Kit
IFNA2 ELISA Kit for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL011038HU | Human interferon alpha-2(IFNA2) ELISA kit | serum, plasma, cell culture supernates, tissue homogenates | 7.8 pg/ml. |
IFNA2 ELISA Kit for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL011038MO | Mouse interferon alpha-2(IFNA2) ELISA kit | serum, plasma, tissue homogenates, cell lysates | 2.35 pg/mL |
