IFI16
Gamma-interferon-inducible protein 16 is a protein in humans that is encoded by IFI16 gene. Binds double-stranded DNA. Binds preferentially to supercoiled DNA and cruciform DNA structures. Seems to be involved in transcriptional regulation. May function as a transcriptional repressor. Could have a role in the regulation of hematopoietic differentiation through activation of unknown target genes. Controls cellular proliferation by modulating the functions of cell cycle regulatory factors including p53/TP53 and the retinoblastoma protein. May be involved in TP53-mediated transcriptional activation by enhancing TP53 sequence-specific DNA binding and modulating TP53 phosphorylation status. Seems to be involved in energy-level-dependent activation of the ATM/ AMPK/TP53 pathway coupled to regulation of autophagy.
IFI16 Antibodies
IFI16 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA586413 | IFI16 Antibody | Human | ELISA,WB |
| CSB-PA009445 | IFI16 Antibody | Human | WB, ELISA |
IFI16 Proteins
IFI16 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP620975HU CSB-EP620975HU CSB-BP620975HU CSB-MP620975HU CSB-EP620975HU-B |
Recombinant Human Gamma-interferon-inducible protein 16 (IFI16) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IFI16 Proteins for Pongo abelii (Sumatran orangutan)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP719265PYX CSB-EP719265PYX CSB-BP719265PYX CSB-MP719265PYX CSB-EP719265PYX-B |
Recombinant Pongo abelii Gamma-interferon-inducible protein 16 (IFI16), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
