HSPA1A

HSPA1A，全稱為熱休克蛋白家族A成員1A（Heat Shock Protein Family A Member 1A），是一種重要的分子伴侶，在細胞應激反應中發(fā)揮著關鍵作用。它能夠幫助蛋白質(zhì)正確折疊，修復錯誤折疊的蛋白質(zhì)，并促進蛋白質(zhì)復合物的形成與解離，從而維護蛋白質(zhì)組的完整性。HSPA1A蛋白也參與了細胞內(nèi)的信號傳導過程，影響細胞的生長、分化和凋亡。
HSPA1A蛋白的表達水平與多種疾病相關，如癌癥、神經(jīng)退行性疾病和感染性疾病等。近年來，HSPA1A蛋白成為藥物研發(fā)的一個熱點，研究人員正在探索其作為治療癌癥、神經(jīng)退行性疾病和感染性疾病的潛在靶點。例如，有研究顯示，HSPA1A蛋白可以抑制腫瘤細胞的增殖和轉(zhuǎn)移，并促進腫瘤細胞的凋亡。此外，HSPA1A蛋白還可以增強免疫細胞的功能，幫助身體抵抗感染。因此，HSPA1A蛋白有望成為開發(fā)新型抗癌藥物和治療感染性疾病的潛在靶點。

熱銷產(chǎn)品

HSPA1A/HSPA1B Recombinant Monoclonal Antibody (CSB-RA151186A0HU)

驗證數(shù)據(jù)

Western Blot
Positive WB detected in: HEK293 whole cell lysate(30μg), U937 whole cell lysate(30μg), NIH/3T3 whole cell lysate(30μg)
All lanes: Hsp70 antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 70 kDa
Observed band size: 70 kDa
Exposure time: 3min

IHC image of CSB-RA151186A0HU diluted at 1:100 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB.

Overlay Peak curve showing Hela cells stained with CSB-RA151186A0HU (red line) at 1:100. The cells were fixed in 4% formaldehyde and permeated by 0.2% TritonX-100 for?10min. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1ug/1*10⁶cells) for 45min at 4℃. The secondary antibody used was FITC-conjugated goat anti-rabbit IgG (H+L) at 1/200 dilution for 35min at 4℃.Control antibody (green line) was Rabbit IgG (1ug/1*10⁶cells) used under the same conditions. Acquisition of >10,000 events was performed.

Human Heat Shock Protein 72(HSP-72) ELISA Kit (CSB-E14916h)

驗證數(shù)據(jù)

貨號：CSB-E14916h

規(guī)格：96T/48T

靈敏度：0.78 ng/mL

檢測范圍：3.12 ng/mL-200 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

HSPA1A Antibody

HSPA1A ELISA Kit

HSPA1A Antibodies

HSPA1A for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應性	應用類型
CSB-PA01082GA01HU	HSPA1A Antibody	Human,Mouse,Rat	ELISA,WB,IHC,IF
CSB-PA556911	HSPA1A Antibody	Human,Mouse,Rat	ELISA,IHC
CSB-PA137102	HSPA1A Antibody	Human,Mouse,Rat	ELISA,IHC
CSB-PA10899A0Rb	HSPA1A Antibody	Human	ELISA, WB, IHC, IF
CSB-PA10899B0Rb	HSPA1A Antibody, HRP conjugated	Human	ELISA
CSB-PA10899C0Rb	HSPA1A Antibody, FITC conjugated	Human
CSB-PA10899D0Rb	HSPA1A Antibody, Biotin conjugated	Human	ELISA
CSB-PA357302LA01HU	HSPA1A Antibody	Human	ELISA, WB, IHC
CSB-PA357302LB01HU	HSPA1A Antibody, HRP conjugated	Human	ELISA
CSB-PA357302LC01HU	HSPA1A Antibody, FITC conjugated	Human
CSB-PA357302LD01HU	HSPA1A Antibody, Biotin conjugated	Human	ELISA
CSB-MA357302A0m	HSPA1A Monoclonal Antibody	Human	ELISA, WB