HLA-DQA2
HLA class II histocompatibility antigen, DQ alpha 2 chain is a protein in humans that is encoded by HLA-DQA2 gene. Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molecules are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Exogenous antigens that have been endocytosed by the APC are thus readily available for presentation via MHC II molecules, and for this reason this antigen presentation pathway is usually referred to as exogenous. As membrane proteins on their way to degradation in lysosomes as part of their normal turn-over are also contained in the endosomal/lysosomal compartments, exogenous antigens must compete with those derived from endogenous components.
HLA-DQA2 Antibodies
HLA-DQA2 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA14829A0Rb | HLA-DQA2 Antibody | Human | ELISA, IHC |
HLA-DQA2 Proteins
HLA-DQA2 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP010493HU CSB-EP010493HU CSB-BP010493HU CSB-MP010493HU CSB-EP010493HU-B |
Recombinant Human HLA class II histocompatibility antigen, DQ alpha 2 chain (HLA-DQA2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-RP148294h | Recombinant Human HLA class II histocompatibility antigen, DQ alpha 2 chain (HLA-DQA2), partial | E.coli |
| CSB-CF010493HU | Recombinant Human HLA class II histocompatibility antigen, DQ alpha 2 chain (HLA-DQA2) | in vitro E.coli expression system |
