GPR161
G-protein coupled receptor 161 is a protein in humans that is encoded by GPR161 gene. Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling. In presence of SHH, it is removed from primary cilia and is internalized into recycling endosomes, preventing its activity and allowing activation of the Shh signaling. Its ligand is unknown (By similarity).
GPR161 Antibodies
GPR161 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA04114A0Rb | GPR161 Antibody | Human | ELISA, WB, IF |
| CSB-PA04114C0Rb | GPR161 Antibody, FITC conjugated | Human | |
| CSB-PA009774GA01HU | GPR161 Antibody | Human,Mouse,Rat | ELISA,WB |
GPR161 Proteins
GPR161 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP009774MO1 CSB-EP009774MO1 CSB-BP009774MO1 CSB-MP009774MO1 CSB-EP009774MO1-B |
Recombinant Mouse G-protein coupled receptor 161 (Gpr161), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF009774MO | Recombinant Mouse G-protein coupled receptor 161 (Gpr161) | in vitro E.coli expression system |
GPR161 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-RP041144h | Recombinant Human G-protein coupled receptor 161 (GPR161), partial | E.coli |
| CSB-YP836681HU CSB-EP836681HU CSB-BP836681HU CSB-MP836681HU CSB-EP836681HU-B |
Recombinant Human G-protein coupled receptor 161 (GPR161), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF836681HU | Recombinant Human G-protein coupled receptor 161 (GPR161) | in vitro E.coli expression system |
GPR161 Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP009774XBF1 CSB-EP009774XBF1 CSB-BP009774XBF1 CSB-MP009774XBF1 CSB-EP009774XBF1-B |
Recombinant Xenopus tropicalis G-protein coupled receptor 161 (gpr161), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF009774XBF | Recombinant Xenopus tropicalis G-protein coupled receptor 161 (gpr161) | in vitro E.coli expression system |
GPR161 Proteins for Bos taurus (Bovine)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP009774BO1 CSB-EP009774BO1 CSB-BP009774BO1 CSB-MP009774BO1 CSB-EP009774BO1-B |
Recombinant Bovine G protein-coupled receptor 161 (GPR161), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF009774BO | Recombinant Bovine G protein-coupled receptor 161 (GPR161) | in vitro E.coli expression system |
GPR161 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP820893DIL1 CSB-EP820893DIL1 CSB-BP820893DIL1 CSB-MP820893DIL1 CSB-EP820893DIL1-B |
Recombinant Danio rerio G-protein coupled receptor 161 (gpr161), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF820893DIL | Recombinant Danio rerio G-protein coupled receptor 161 (gpr161) | in vitro E.coli expression system |
