GPR119
GPR119，即G蛋白偶聯受體119，別名Glucose-dependent insulinotropic receptor，是一種G蛋白偶聯受體（GPCR）超家族中的孤兒受體，主要分布在胰島β細胞和胃腸道L細胞。GPR119的作用機制是通過與內源性配體如油酰乙醇酰胺和其他含有油酸的內源性脂質結合來激活，進而刺激胰高血糖素樣肽-1（GLP-1）和葡萄糖依賴性促胰島素釋放多肽（GIP）的分泌，這兩種激素對于調控體內糖代謝平衡具有重要作用。GPR119的激活可以促進葡萄糖依賴的胰島素分泌，增加腸道分泌的腸促胰島素激素，是治療糖尿病、脂肪肝和肥胖癥等代謝性疾病的潛在藥物靶點。
熱銷產品
GPR119 Antibody (CSB-PA007283)
驗證數據
Western Blot analysis of COLO cells using GPR119 Polyclonal Antibody
Western blot analysis of SH-SY5Y mouse-kidney lysis using GPR119 antibody.
GPR119 Antibodies
GPR119 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA007283 | GPR119 Antibody | Human | WB, IF, ELISA |
GPR119 Proteins
GPR119 Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP752652RA1 CSB-EP752652RA1 CSB-BP752652RA1 CSB-MP752652RA1 CSB-EP752652RA1-B |
Recombinant Rat Glucose-dependent insulinotropic receptor (Gpr119), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF752652RA | Recombinant Rat Glucose-dependent insulinotropic receptor (Gpr119) | in vitro E.coli expression system |
GPR119 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP766514MO1 CSB-EP766514MO1 CSB-BP766514MO1 CSB-MP766514MO1 CSB-EP766514MO1-B |
Recombinant Mouse Glucose-dependent insulinotropic receptor (Gpr119), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF766514MO | Recombinant Mouse Glucose-dependent insulinotropic receptor (Gpr119) | in vitro E.coli expression system |
GPR119 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP840575HU1 CSB-EP840575HU1 CSB-BP840575HU1 CSB-MP840575HU1 CSB-EP840575HU1-B |
Recombinant Human Glucose-dependent insulinotropic receptor (GPR119), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF840575HU | Recombinant Human Glucose-dependent insulinotropic receptor (GPR119) | in vitro E.coli expression system |
