G3BP1
G3BP1 is a protein in humans that is encoded by G3BP1 gene. ATP- and magnesium-dependent helicase that plays an essential role in innate immunity. Participates in the DNA-triggered cGAS/STING pathway by promoting the DNA binding and activation of CGAS. Enhances also DDX58-induced type I interferon production probably by helping DDX58 at sensing pathogenic RNA. In addition, plays an essential role in stress granule formation. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR.
G3BP1 Antibodies
G3BP1 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA009116GA01HU | G3BP1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
| CSB-PA613389ESR1HU | G3BP1 Antibody | Human | ELISA, WB, IHC |
| CSB-PA908450 | Phospho-G3BP1 (Ser232) Antibody | Human | ELISA,WB,IHC,IF |
| CSB-PA057449 | G3BP1 (Ab-232) Antibody | Human | ELISA,WB,IHC |
| CSB-PA000531 | Phospho-G3BP1 (S232) Antibody | Human,Mouse | WB, IHC, ELISA |
| CSB-PA002599 | G3BP1 Antibody | Human,Mouse,Monkey | WB, IHC, ELISA |
G3BP1 Proteins
G3BP1 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP009116MO CSB-EP009116MO CSB-BP009116MO CSB-MP009116MO CSB-EP009116MO-B |
Recombinant Mouse Ras GTPase-activating protein-binding protein 1 (G3bp1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
G3BP1 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP613389HU CSB-EP613389HU CSB-BP613389HU CSB-MP613389HU CSB-EP613389HU-B |
Recombinant Human Ras GTPase-activating protein-binding protein 1 (G3BP1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP613389HU(A4)a0 | Recombinant Human Ras GTPase-activating protein-binding protein 1 (G3BP1) | E.coli |
G3BP1 Proteins for Bos taurus (Bovine)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP654171BO CSB-EP654171BO CSB-BP654171BO CSB-MP654171BO CSB-EP654171BO-B |
Recombinant Bovine Ras GTPase-activating protein-binding protein 1 (G3BP) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
G3BP1 Proteins for Pongo abelii (Sumatran orangutan)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP712947PYX CSB-EP712947PYX CSB-BP712947PYX CSB-MP712947PYX CSB-EP712947PYX-B |
Recombinant Pongo abelii Ras GTPase-activating protein-binding protein 1 (G3BP1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
