FOLH1

FOLH1，即葉酸水解酶1，別名 Cell growth inhibiting protein 27 、Folate hydrolase 1、Folate hydrolase，是一種關(guān)鍵的葉酸代謝酶。它由FOLH1基因編碼，分布在前列腺、腦、肺、肝等多種組織中。FOLH1通過水解葉酸多聚谷氨酸鹽，調(diào)節(jié)細(xì)胞內(nèi)葉酸水平，對(duì)DNA合成和修復(fù)至關(guān)重要。其異常表達(dá)與前列腺癌等腫瘤的發(fā)生發(fā)展關(guān)聯(lián)，使其成為潛在的治療靶點(diǎn)。此外，F(xiàn)OLH1在神經(jīng)退行性疾病中也有研究?jī)r(jià)值，其活性變化可能與多巴胺神經(jīng)元損失有關(guān)，對(duì)細(xì)胞代謝和增殖具有重要調(diào)控作用。

熱銷產(chǎn)品

Recombinant Human Glutamate carboxypeptidase 2 (FOLH1), partial (Active) (CSB-MP008782HU1)

驗(yàn)證數(shù)據(jù)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Activity
Measured by its binding ability in a functional ELISA.Immobilized Human FOLH1 at 2 μg/ml can bind Anti-FOLH1 recombinant antibody(CSB-RA008782MA1HU). The EC₅₀ is 11.74-15.02 ng/mL.

Activity
Measured by its binding ability in a functional ELISA.Immobilized Human FOLH1 at 2 μg/mL can bind Anti-FOLH1 recombinant antibody(CSB-RA008782MA2HU). The EC50 is 3.853-4.303 ng/mL.

FOLH1 Recombinant Monoclonal Antibody (CSB-RA162924A0HU)

驗(yàn)證數(shù)據(jù)

IHC image of CSB-RA162924A0HU diluted at 1:100 and staining in paraffin-embedded human prostate cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

Human Glutamate carboxypeptidase 2(FOLH1) ELISA kit (CSB-EL008782HU)

驗(yàn)證數(shù)據(jù)

貨號(hào)：CSB-EL008782HU

規(guī)格：96T/48T

靈敏度：1.2 ng/mL

檢測(cè)范圍：4.7 ng/mL-300 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

FOLH1 Antibody

FOLH1 Protein

FOLH1 ELISA Kit

FOLH1 Antibodies

FOLH1 for Homo sapiens (Human)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA11729A0Rb	FOLH1 Antibody	Human	ELISA, WB, IHC
CSB-PA11729B0Rb	FOLH1 Antibody, HRP conjugated	Human	ELISA
CSB-PA11729D0Rb	FOLH1 Antibody, Biotin conjugated	Human	ELISA
CSB-PA008782GA01HU	FOLH1 Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA167493	FOLH1 Antibody	Human	ELISA,WB
CSB-RA162924A0HU	FOLH1 Recombinant Monoclonal Antibody	Human	ELISA, IHC

FOLH1 Proteins

FOLH1 Proteins for Rattus norvegicus (Rat)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP008782RA1 CSB-EP008782RA1 CSB-BP008782RA1 CSB-MP008782RA1 CSB-EP008782RA1-B	Recombinant Rat Glutamate carboxypeptidase 2 (Folh1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF008782RA	Recombinant Rat Glutamate carboxypeptidase 2 (Folh1)	in vitro E.coli expression system

FOLH1 Proteins for Homo sapiens (Human)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP008782HU CSB-BP008782HU CSB-MP008782HU CSB-EP008782HU-B	Recombinant Human Glutamate carboxypeptidase 2 (FOLH1), partial	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP008782HU	Recombinant Human Glutamate carboxypeptidase 2 (FOLH1), partial	E.coli
CSB-CF008782HU(A4)	Recombinant Human Glutamate carboxypeptidase 2 (FOLH1)	in vitro E.coli expression system

FOLH1 Proteins for Mus musculus (Mouse)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP008782MO1 CSB-EP008782MO1 CSB-BP008782MO1 CSB-MP008782MO1 CSB-EP008782MO1-B	Recombinant Mouse Glutamate carboxypeptidase 2 (Folh1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF008782MO	Recombinant Mouse Glutamate carboxypeptidase 2 (Folh1)	in vitro E.coli expression system

FOLH1 Proteins for Sus scrofa (Pig)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP008782PI1 CSB-EP008782PI1 CSB-BP008782PI1 CSB-EP008782PI1-B	Recombinant Pig Glutamate carboxypeptidase 2 (FOLH1), partial	Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli
CSB-CF008782PI	Recombinant Pig Glutamate carboxypeptidase 2 (FOLH1)	in vitro E.coli expression system