FBXO2
F-box only protein 2is a protein in humans that is encoded by FBXO2 gene. Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Involved in the endoplasmic reticulum-associated degradation pathway (ERAD) for misfolded lumenal proteins by recognizing and binding sugar chains on unfolded glycoproteins that are retrotranslocated into the cytosol and promoting their ubiquitination and subsequent degradation. Prevents formation of cytosolic aggregates of unfolded glycoproteins that have been retrotranslocated into the cytosol. Able to recognize and bind denatured glycoproteins, preferentially those of the high-mannose type (By similarity).
FBXO2 Antibodies
FBXO2 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA008487GA01HU | FBXO2 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA892326ESR1HU | FBXO2 Antibody | Human | ELISA, IHC |
FBXO2 Proteins
FBXO2 Proteins for Bos taurus (Bovine)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP623160BO CSB-EP623160BO CSB-BP623160BO CSB-MP623160BO CSB-EP623160BO-B |
Recombinant Bovine F-box only protein 2 (FBXO2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FBXO2 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP802228MO CSB-EP802228MO CSB-BP802228MO CSB-MP802228MO CSB-EP802228MO-B |
Recombinant Mouse F-box only protein 2 (Fbxo2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FBXO2 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP892326HU CSB-BP892326HU CSB-MP892326HU CSB-EP892326HU-B |
Recombinant Human F-box only protein 2 (FBXO2) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP892326HU | Recombinant Human F-box only protein 2 (FBXO2) | E.coli |
