F12
F12，全稱為凝血因子XII（Hageman factor），是一種血清糖蛋白，在啟動血液凝固、纖維蛋白溶解以及緩激肽和血管緊張素的生成中發(fā)揮多方面的作用。F12蛋白也被稱為F12因子、HAE3因子、Factor 12，其EC編號為3.4.21.38。F12蛋白在血液中循環(huán)作為酶原，在遇到帶負(fù)電的表面或錯誤折疊的蛋白質(zhì)聚集物時被激活，進(jìn)而參與內(nèi)源性凝血途徑，促進(jìn)血液凝固。F12蛋白還參與激肽系統(tǒng)和免疫反應(yīng)，對維持機(jī)體正常生理功能至關(guān)重要。F12蛋白的缺乏通常不會導(dǎo)致明顯的臨床癥狀，但在某些情況下，F(xiàn)12蛋白的異常激活可能與血栓形成和炎癥反應(yīng)有關(guān)。目前，針對F12蛋白的藥物研發(fā)尚處于早期階段，但已有研究表明，抑制F12蛋白的活性可能有助于預(yù)防和治療血栓性疾病和炎癥性疾病。
熱銷產(chǎn)品
Recombinant Human Coagulation factor XII (F12), partial (CSB-EP007918HU)
驗證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
F12 Antibody (CSB-PA007918LA01HU)
驗證數(shù)據(jù)
Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA007918LA01HU at dilution of 1:100
F12 Antibodies
F12 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA007918GA01HU | F12 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA000068 | Cleaved-F12 (R372) Antibody | Human | WB, ELISA |
| CSB-PA008169 | Cleaved-F12 (I20) Antibody | Human | WB, IHC, ELISA |
| CSB-PA007918LA01HU | F12 Antibody | Human | ELISA, IHC |
| CSB-PA007918LB01HU | F12 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA007918LC01HU | F12 Antibody, FITC conjugated | Human | |
| CSB-PA007918LD01HU | F12 Antibody, Biotin conjugated | Human | ELISA |
F12 for Pig
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA007918LA01PI | F12 Antibody | Pig | ELISA |
| CSB-PA007918LB01PI | F12 Antibody, HRP conjugated | Pig | ELISA |
| CSB-PA007918LC01PI | F12 Antibody, FITC conjugated | Pig | |
| CSB-PA007918LD01PI | F12 Antibody, Biotin conjugated | Pig | ELISA |
F12 Proteins
F12 Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP007918BO CSB-EP007918BO CSB-BP007918BO CSB-MP007918BO CSB-EP007918BO-B |
Recombinant Bovine Coagulation factor XII (F12) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
F12 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP007918RA CSB-EP007918RA CSB-BP007918RA CSB-MP007918RA CSB-EP007918RA-B |
Recombinant Rat Coagulation factor XII (F12), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
F12 Proteins for Sus scrofa (Pig)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP007918PI | Recombinant Pig Coagulation factor XII (F12), partial | Yeast |
| CSB-EP007918PI | Recombinant Pig Coagulation factor XII (F12), partial | E.coli |
| CSB-BP007918PI CSB-MP007918PI CSB-EP007918PI-B |
Recombinant Pig Coagulation factor XII (F12), partial | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
F12 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP007918HU CSB-BP007918HU CSB-MP007918HU CSB-EP007918HU-B |
Recombinant Human Coagulation factor XII (F12), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP007918HU | Recombinant Human Coagulation factor XII (F12), partial | E.coli |
F12 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP802255MO CSB-EP802255MO CSB-BP802255MO CSB-MP802255MO CSB-EP802255MO-B |
Recombinant Mouse Coagulation factor XII (F12), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
