ESR1
ESR1，即雌激素受體1，別名核受體亞型1（NR3A1）、雌激素受體α等。它是一種核受體超家族成員，由人體細(xì)胞自身的基因編碼。ESR1主要在乳腺、子宮、骨骼、心血管系統(tǒng)等多種組織中表達(dá)，并且在維持這些組織的生理功能中發(fā)揮關(guān)鍵作用。ESR1的作用機(jī)制涉及與雌激素結(jié)合后，促進(jìn)受體的二聚化和核內(nèi)轉(zhuǎn)位，進(jìn)而與DNA上的雌激素應(yīng)答元件（ERE）結(jié)合，調(diào)控下游基因的轉(zhuǎn)錄。此外，ESR1也可以通過(guò)非基因組途徑快速響應(yīng)，影響細(xì)胞內(nèi)的信號(hào)傳導(dǎo)。ESR1在生物學(xué)上的意義非常廣泛，它不僅參與調(diào)節(jié)生殖系統(tǒng)的發(fā)育和功能，還與骨骼健康、心血管保護(hù)、神經(jīng)保護(hù)以及免疫調(diào)節(jié)等過(guò)程密切相關(guān)。ESR1信號(hào)通路的激活可以促進(jìn)細(xì)胞增殖、分化，同時(shí)也影響細(xì)胞周期和凋亡。在疾病方面，ESR1的功能異常與多種疾病相關(guān)，尤其是乳腺癌，其中ESR1的過(guò)表達(dá)或信號(hào)通路的異常激活是乳腺癌發(fā)生發(fā)展的重要因素之一。因此，ESR1是內(nèi)分泌治療和相關(guān)疾病研究中的一個(gè)重要靶點(diǎn)。
熱銷產(chǎn)品
Recombinant Human Estrogen receptor (ESR1), partial (CSB-YP007830HU1)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
ESR1 Recombinant Monoclonal Antibody (CSB-RA172909A0HU)
驗(yàn)證數(shù)據(jù)
Western Blot
Positive WB detected in: NIH/3T3 whole cell lysate, SH-SY5Y whole cell lysate, U-87 whole cell lysate
All lanes: Estrogen Receptor alpha antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 67, 54, 48, 36 kDa
Observed band size: 67 kDa
ESR1 Antibodies
ESR1 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA11399D0Rb | ESR1 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA11399B0Rb | ESR1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA007830YA01HU | ESR1 Antibody | Human | ELISA, IHC, IF |
| CSB-PA007830YC01HU | ESR1 Antibody, FITC conjugated | Human | |
| CSB-PA007830YD01HU | ESR1 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA11399C0Rb | ESR1 Antibody, FITC conjugated | Human | |
| CSB-PA858084 | Phospho-ESR1 (Ser104) Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA080696 | Phospho-ESR1 (Ser106) Antibody | Human,Mouse | ELISA,WB,IHC,IF |
| CSB-PA828752 | Phospho-ESR1 (Ser118) Antibody | Human,Mouse,Monkey | ELISA,WB,IHC,IF |
| CSB-PA041340 | Phospho-ESR1 (Ser167) Antibody | Human,Mouse | ELISA,WB,IHC,IF |
| CSB-PA569446 | ESR1 (Ab-104) Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA209007 | ESR1 (Ab-106) Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA696439 | ESR1 (Ab-118) Antibody | Human,Mouse | ELISA,WB,IHC,IF |
| CSB-PA956111 | ESR1 (Ab-167) Antibody | Human,Mouse | ELISA,WB,IHC,IF |
| CSB-PA265011 | Phospho-ESR1 (Tyr537) Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA047787 | Phospho-ESR1 (Ser102) Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA951647 | ESR1 (Ab-537) Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA000524 | Phospho-ESR1 (S104) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA000525 | Phospho-ESR1 (S118) Antibody | Human,Mouse | WB, IHC, ELISA |
| CSB-PA002436 | ESR1 Antibody | Human | WB, IHC, ELISA |
| CSB-PA002442 | ESR1 Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA005470 | ESR1 Antibody | Human | WB, ELISA |
| CSB-PA008137 | Phospho-ESR1 (S106) Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA008140 | Phospho-ESR1 (S167) Antibody | Human | WB, IHC, ELISA |
| CSB-PA008141 | Phospho-ESR1 (Y537) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA008145 | Phospho-ESR1 (S102) Antibody | Human,Mouse,Rat | IHC, ELISA |
| CSB-PA008146 | Phospho-ESR1 (S305) Antibody | Human | IF, ELISA |
| CSB-PA008147 | ESR1 Antibody | Human,Mouse | WB, IHC, ELISA |
| CSB-PA008148 | ESR1 Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA080277 | ESR1 Antibody | Human,Mouse,Rat | WB |
| CSB-PA980849 | ESR1 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA223323 | ESR1 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA11399A0Rb | ESR1 Antibody | Human, Rat | ELISA, WB, IHC, ChIP |
| CSB-RA007830A118phHU | Phospho-ESR1 (S118) Recombinant Monoclonal Antibody | Human | ELISA, IHC |
| CSB-MA442659 | ESR1 Monoclonal Antibody | Human | ELISA, IHC |
| CSB-RA942338A0HU | ESR1 Recombinant Monoclonal Antibody | Human | ELISA, IHC |
| CSB-RA172909A0HU | ESR1 Recombinant Monoclonal Antibody | Human, Mouse | ELISA, WB |
ESR1 Proteins
ESR1 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP007830MO CSB-EP007830MO CSB-BP007830MO CSB-MP007830MO |
Recombinant Mouse Estrogen receptor (Esr1) | Yeast E.coli Baculovirus Mammalian cell |
ESR1 Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP007830BO CSB-EP007830BO CSB-BP007830BO CSB-MP007830BO CSB-EP007830BO-B |
Recombinant Bovine Estrogen receptor (ESR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ESR1 Proteins for Ovis aries (Sheep)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP007830SH CSB-EP007830SH CSB-BP007830SH CSB-MP007830SH CSB-EP007830SH-B |
Recombinant Sheep Estrogen receptor (ESR1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ESR1 Proteins for Macaca mulatta (Rhesus macaque)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP007830MOW CSB-EP007830MOW CSB-BP007830MOW CSB-MP007830MOW CSB-EP007830MOW-B |
Recombinant Macaca mulatta (Rhesus macaque) Estrogen receptor (ESR1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ESR1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP007830HU | Recombinant Human Estrogen receptor (ESR1), partial | Yeast |
| CSB-YP007830HU1 | Recombinant Human Estrogen receptor (ESR1), partial | Yeast |
ESR1 Proteins for Gallus gallus (Chicken)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP007830CH CSB-EP007830CH CSB-BP007830CH CSB-MP007830CH CSB-EP007830CH-B |
Recombinant Chicken Estrogen receptor (ESR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ESR1 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP007830RA CSB-EP007830RA CSB-BP007830RA CSB-MP007830RA CSB-EP007830RA-B |
Recombinant Rat Estrogen receptor (Esr1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ESR1 Proteins for Xenopus laevis (African clawed frog)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP007830XBE CSB-EP007830XBE CSB-BP007830XBE CSB-MP007830XBE CSB-EP007830XBE-B |
Recombinant Xenopus laevis Estrogen receptor (esr1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ESR1 Proteins for Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP007830OEI CSB-EP007830OEI CSB-BP007830OEI CSB-MP007830OEI CSB-EP007830OEI-B |
Recombinant Oncorhynchus mykiss Estrogen receptor (esr1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ESR1 Proteins for Oreochromis aureus (Israeli tilapia) (Chromis aureus)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP007830OCB CSB-EP007830OCB CSB-BP007830OCB CSB-MP007830OCB CSB-EP007830OCB-B |
Recombinant Oreochromis aureus Estrogen receptor (esr1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ESR1 Proteins for Oryzias latipes (Medaka fish) (Japanese ricefish)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP007830OFH CSB-EP007830OFH CSB-BP007830OFH CSB-MP007830OFH CSB-EP007830OFH-B |
Recombinant Oryzias latipes Estrogen receptor (esr1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ESR1 Proteins for Salmo salar (Atlantic salmon)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP007830SWI CSB-EP007830SWI CSB-BP007830SWI CSB-MP007830SWI CSB-EP007830SWI-B |
Recombinant Salmo salar Estrogen receptor (esr1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ESR1 Proteins for Micropogonias undulatus (Atlantic croaker)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP007830MGH CSB-EP007830MGH CSB-BP007830MGH CSB-MP007830MGH CSB-EP007830MGH-B |
Recombinant Micropogonias undulatus Estrogen receptor (esr1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ESR1 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP007830DIL CSB-EP007830DIL CSB-BP007830DIL CSB-MP007830DIL CSB-EP007830DIL-B |
Recombinant Danio rerio Estrogen receptor (esr1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ESR1 Proteins for Pagrus major (Red sea bream) (Chrysophrys major)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP007830EQR CSB-EP007830EQR CSB-BP007830EQR CSB-MP007830EQR CSB-EP007830EQR-B |
Recombinant Pagrus major Estrogen receptor (esr1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ESR1 Proteins for Zea mays (Maize)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP521313ZAX CSB-EP521313ZAX CSB-BP521313ZAX CSB-MP521313ZAX CSB-EP521313ZAX-B |
Recombinant Zea mays CLAVATA3/ESR (CLE)-related protein ESR1 (ESR1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ESR1 Proteins for Sus scrofa (Pig)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP640887PI CSB-EP640887PI CSB-BP640887PI CSB-MP640887PI CSB-EP640887PI-B |
Recombinant Pig Estrogen receptor (ESR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ESR1 Proteins for Felis catus (Cat) (Felis silvestris catus)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP687486CA CSB-EP687486CA CSB-BP687486CA CSB-MP687486CA CSB-EP687486CA-B |
Recombinant Cat Estrogen receptor (ESR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ESR1 Proteins for Taeniopygia guttata (Zebra finch) (Poephila guttata)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP838604TKW CSB-EP838604TKW CSB-BP838604TKW CSB-MP838604TKW CSB-EP838604TKW-B |
Recombinant Taeniopygia guttata Estrogen receptor (ESR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ESR1 Proteins for Cnemidophorus uniparens (Desert grassland whiptail lizard)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP852710CLAZ CSB-EP852710CLAZ CSB-BP852710CLAZ CSB-MP852710CLAZ CSB-EP852710CLAZ-B |
Recombinant Cnemidophorus uniparens Estrogen receptor (ESR1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ESR1 Proteins for Sparus aurata (Gilthead sea bream)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP868712FJX CSB-EP868712FJX CSB-BP868712FJX CSB-MP868712FJX CSB-EP868712FJX-B |
Recombinant Sparus aurata Estrogen receptor (esr1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ESR1 Proteins for Arabidopsis thaliana (Mouse-ear cress)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP882808DOA CSB-EP882808DOA CSB-BP882808DOA CSB-MP882808DOA CSB-EP882808DOA-B |
Recombinant Arabidopsis thaliana Ethylene-responsive transcription factor ESR1 (ESR1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ESR1 Proteins for Mesocricetus auratus (Golden hamster)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP886402MRG CSB-EP886402MRG CSB-BP886402MRG CSB-MP886402MRG CSB-EP886402MRG-B |
Recombinant Mesocricetus auratus Estrogen receptor (ESR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ESR1 Proteins for Equus caballus (Horse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP886955HO CSB-EP886955HO CSB-BP886955HO CSB-MP886955HO CSB-EP886955HO-B |
Recombinant Horse Estrogen receptor (ESR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ESR1 Proteins for Anolis carolinensis (Green anole) (American chameleon)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP897424AKP CSB-EP897424AKP CSB-BP897424AKP CSB-MP897424AKP CSB-EP897424AKP-B |
Recombinant Anolis carolinensis Estrogen receptor (ESR1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ESR1 ELISA Kit
ESR1 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E08652h | Human Estradiol receptor,ER ELISA Kit | serum, plasma, tissue homogenates, cell lysates | 0.78 pg/mL |
ESR1 ELISA Kit for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E06848r | rat Estradiol receptor,ER ELISA Kit | serum, plasma, tissue homogenates, cell lysates | 7.81 pg/mL |
