DRD3
DRD3，即多巴胺受體D3，別名D(3 dopamine receptor、Dopamine D3 receptor。它是一種G蛋白偶聯(lián)受體，屬于多巴胺受體家族成員之一，由人體細(xì)胞自身的DRD3基因編碼。DRD3主要在大腦的邊緣區(qū)域表達(dá)，與認(rèn)知、情緒和內(nèi)分泌功能相關(guān)。其作用機(jī)制是通過與G蛋白相互作用，抑制腺苷酸環(huán)化酶的活性，進(jìn)而影響細(xì)胞內(nèi)的信號傳遞。DRD3參與調(diào)節(jié)多種生理過程，包括運(yùn)動控制、情緒反應(yīng)、認(rèn)知功能以及內(nèi)分泌調(diào)節(jié)等。此外，DRD3的異常表達(dá)或功能與多種神經(jīng)精神疾病有關(guān)，如精神分裂癥、帕金森病、不安腿綜合癥、藥物依賴等。研究表明，遺傳變異在DRD3基因可能與某些疾病的易感性相關(guān)，例如遺傳性特發(fā)性震顫。因此，DRD3是神經(jīng)科學(xué)研究和相關(guān)疾病治療中的一個(gè)潛在靶點(diǎn)。
熱銷產(chǎn)品
DRD3 Recombinant Monoclonal Antibody (CSB-RA929304A0HU)
驗(yàn)證數(shù)據(jù)
Western Blot
Positive WB detected in: Hela whole cell lysate, U-251 whole cell lysate, U-87 whole cell lysate, K562 whole cell lysate, HL-60 whole cell lysate, Rat Spleen whole cell lysate, Rat Brain whole cell lysate
All lanes: Dopamine Receptor D3 antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 45, 41 kDa
Observed band size: 50 kDa
DRD3 Antibodies
DRD3 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA007180ESR1HU | DRD3 Antibody | Human | ELISA, IHC |
| CSB-PA007180ESR2HU | DRD3 Antibody | Human | ELISA, WB, IHC |
| CSB-PA005795 | DRD3 Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-RA929304A0HU | DRD3 Recombinant Monoclonal Antibody | Human, Rat | ELISA, WB |
DRD3 Proteins
DRD3 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP007180RA1 CSB-EP007180RA1 CSB-BP007180RA1 CSB-MP007180RA1 CSB-EP007180RA1-B |
Recombinant Rat D (3) dopamine receptor (Drd3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF007180RA | Recombinant Rat D (3) dopamine receptor (Drd3) | in vitro E.coli expression system |
DRD3 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP007180HU1 CSB-EP007180HU1 CSB-BP007180HU1 CSB-MP007180HU1 CSB-EP007180HU1-B |
Recombinant Human D (3) dopamine receptor (DRD3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF007180HU | Recombinant Human D (3) dopamine receptor (DRD3) | in vitro E.coli expression system |
DRD3 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP007180MO1 CSB-EP007180MO1 CSB-BP007180MO1 CSB-MP007180MO1 CSB-EP007180MO1-B |
Recombinant Mouse D (3) dopamine receptor (Drd3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF007180MO | Recombinant Mouse D (3) dopamine receptor (Drd3) | in vitro E.coli expression system |
DRD3 Proteins for Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP345226DSU1 CSB-EP345226DSU1 CSB-BP345226DSU1 CSB-MP345226DSU1 CSB-EP345226DSU1-B |
Recombinant Chlorocebus aethiops D (3) dopamine receptor, partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF345226DSU | Recombinant Chlorocebus aethiops D (3) dopamine receptor | in vitro E.coli expression system |
DRD3 Proteins for Pan troglodytes (Chimpanzee)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP705446EQV1 CSB-EP705446EQV1 CSB-BP705446EQV1 CSB-MP705446EQV1 CSB-EP705446EQV1-B |
Recombinant Pan troglodytes D (3) dopamine receptor (DRD3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF705446EQV | Recombinant Pan troglodytes D (3) dopamine receptor (DRD3) | in vitro E.coli expression system |
