DDIT4
DNA damage-inducible transcript 4 protein is a protein in humans that is encoded by DDIT4 gene. Regulates cell growth, proliferation and survival via inhibition of the activity of the mammalian target of rapamycin complex 1 (mTORC1). Inhibition of mTORC1 is mediated by a pathway that involves DDIT4/REDD1, AKT1, the TSC1-TSC2 complex and the GTPase RHEB. Plays an important role in responses to cellular energy levels and cellular stress, including responses to hypoxia and DNA damage. Regulates p53/TP53-mediated apoptosis in response to DNA damage via its effect on mTORC1 activity. Its role in the response to hypoxia depends on the cell type; it mediates mTORC1 inhibition in fibroblasts and thymocytes, but not in hepatocytes (By similarity). Required for mTORC1-mediated defense against viral protein synthesis and virus replication (By similarity).
DDIT4 Antibodies
DDIT4 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA006590GA01HU | DDIT4 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA151075 | DDIT4 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA794556 | DDIT4 Antibody | Human,Mouse,Rat | ELISA,IHC |
DDIT4 Proteins
DDIT4 Proteins for Bos taurus (Bovine)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP600193BO CSB-EP600193BO CSB-BP600193BO CSB-MP600193BO CSB-EP600193BO-B |
Recombinant Bovine DNA damage-inducible transcript 4 protein (DDIT4) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
DDIT4 Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP747406XBF CSB-EP747406XBF CSB-BP747406XBF CSB-MP747406XBF CSB-EP747406XBF-B |
Recombinant Xenopus tropicalis DNA damage-inducible transcript 4 protein (ddit4) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
DDIT4 Proteins for Xenopus laevis (African clawed frog)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP763066XBE CSB-EP763066XBE CSB-BP763066XBE CSB-MP763066XBE CSB-EP763066XBE-B |
Recombinant Xenopus laevis DNA damage-inducible transcript 4 protein (ddit4) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
DDIT4 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP763083DIL CSB-EP763083DIL CSB-BP763083DIL CSB-MP763083DIL CSB-EP763083DIL-B |
Recombinant Danio rerio DNA damage-inducible transcript 4 protein (ddit4) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
DDIT4 Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP823776RA CSB-EP823776RA CSB-BP823776RA CSB-MP823776RA CSB-EP823776RA-B |
Recombinant Rat DNA damage-inducible transcript 4 protein (Ddit4) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
DDIT4 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP863508MO CSB-EP863508MO CSB-BP863508MO CSB-MP863508MO CSB-EP863508MO-B |
Recombinant Mouse DNA damage-inducible transcript 4 protein (Ddit4) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
DDIT4 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP889135HU CSB-EP889135HU CSB-BP889135HU CSB-MP889135HU CSB-EP889135HU-B |
Recombinant Human DNA damage-inducible transcript 4 protein (DDIT4) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
DDIT4 ELISA Kit
DDIT4 ELISA Kit for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL006590HU | Human DNA damage-inducible transcript 4 protein(DDIT4) ELISA kit | serum, tissue homogenates, cell lysates, urine, cerebrospinal fluid (CSF) | 0.039 ng/mL |
